Scientific Imaging: Tertiary lymphoid structures in neuroblastoma.

Research in children's and young people's cancers

Advancing research, accelerating impact 

Children's and young people's (aged 0-24) cancers are fundamentally different from adult cancers. This creates unique challenges for research and translation.

Progress is often slowed by distinct disease biology, small patient populations, high development costs and limited access to shared data, models and infrastructure. As a result, too few promising discoveries become new treatments.

As the UK's largest funder in this field, we bring together researchers, clinicians, industry partners, funders and people affected by cancer to overcome these barriers and accelerate progress for children and young people.

Get in touch with our dedicated team to discuss how you can get involved.

Contact us to learn more

Our strategy for children and young people’s cancers

Transforming outcomes for children and young people requires a different approach. Our strategy turns discoveries into impact by connecting the expertise, resources and partnerships needed to advance promising research.

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Mission-led discovery

Transform our understanding of the biology, drivers and origins of children's and young people's cancers to unlock new treatment opportunities.

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Identifying new therapeutic targets

Discover and validate the biological vulnerabilities to develop more effective, less toxic treatments for children and young people with cancer.

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Investment in treatment development

Provide the expertise, resources and investment needed to de-risk and advance promising therapeutic opportunities.

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Connected ecosystem

Build a world-class, international ecosystem of teams, infrastructure and data to accelerate translation and trials.

Our overarching research strategy

How we’re driving progress

We’ve been accelerating progress into research for children’s and young people’s cancer for more than 50 years and we’re not stopping there. We’re continuing to invest through international programmes and partnerships. Alongside funding research, we provide access to the expertise, infrastructure and specialist capabilities needed to advance promising discoveries towards new treatments.

Our support spans the full research and translation pathway, from discovery science and therapeutic development to clinical research. By connecting people, resources and opportunities across our network of researchers, clinicians, industry partners, funders and specialist facilities, we help accelerate progress for children and young people with cancer.

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Wider translational support

Discover how we can help develop your most promising projects into tools, tests and treatments for people affected by cancer. We offer full support along the translational pathway, including therapeutic discovery, clinical infrastructure and expertise in drug and technology development.

Partner with us

Advancing treatments for children and young people requires collaboration across the international research community. By bringing together complementary expertise, resources and funding, we can tackle challenges that no single organisation can overcome alone.

We work with charities, government funding agencies, academic institutions, researchers and industry partners across the UK and internationally. Get in touch to discuss how we can work together to improve outcomes in children’s and young people with cancer.

Contact us

Collaboration in action

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Stratified Medicine Paediatrics 2 Programme (SMPaeds2)

Together with Children with Cancer UK, we're co-funding this research programme to advance precision medicine for children and young people with blood cancers and solid tumours. This includes cancers affecting the brain, muscle and bone, which can be more difficult to access, diagnose and treat.

Find out more about the programme

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Cancer Grand Challenges

Cancer Grand Challenges is a global cancer research initiative that takes a bold approach to funding research - by uniting global research teams to tackle cancer’s most complex challenges. We co-fund Cancer Grand Challenges, including the teams aiming to find new ways to treat solid tumours in children and young people.

Meet the teams

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SU2C–CRUK paediatric cancer award

We renewed funding for two SU2C–CRUK Paediatric Cancer New Discoveries Challenge award collaborations, which will each receive a further $5m to continue their projects and bring better treatments for children and young people with cancer.

Read about the awards

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Header image credit: Andrea Lampis, The Institute of Cancer Research.