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Stages

Stage 4 womb cancer

The stage of a cancer tells you how big the tumour is and how far it has spread. Stage 4 means the cancer has spread to another area of the body.

Staging system for womb cancer

Doctors use the International Federation of Gynecology and Obstetrics (FIGO) staging system for womb cancer. There are four stages, numbered 1 to 4.

Although a 2023 version of the FIGO system is available, doctors in the UK generally use the 2021 version.

About stage 4 womb cancer

Stage 4 means the cancer has spread to another area of the body. There are 2 categories of stage 4 womb cancer:

  • 4A means the cancer has grown into the bowel or bladder, or both

  • 4B means the cancer has spread to lymph nodes further away, or to other parts of the body, such as the ​​ , ​​  lungs, liver, bones or brain (secondary cancers or metastases), or both

Diagram showing stage 4 womb cancer.

Your doctor might call stage 4 cancer advanced cancer.

Treatment for womb cancer

The stage of your cancer helps your doctor to decide which treatment you need. Treatment also depends on:

  • the type of womb cancer you have

  • how the cancer is likely to behave (the grade)

  • the risk of your cancer coming back after surgery (low, intermediate, high-intermediate, high)

  • whether your cancer has any gene changes (mutations)

  • your general health

  • your preferences

Surgery

Depending on how far your cancer has spread, it may be possible to remove as much of the cancer as possible.

Read about surgery for womb cancer

If you can't have surgery

There are several reasons why you might not have surgery, including:

  • your cancer is too difficult to remove

  • it has spread to areas further away in your body, such as the liver and lungs

  • you are not fit enough for surgery

  • you choose not to have it

You might have one or more of the following treatments:

  • chemotherapy

  • radiotherapy

  • immunotherapy

  • hormone therapy

Your doctor might also suggest you take part in a clinical trial.

Read about hormone treatment

Treatment after surgery

After surgery you may have one of the following treatments:

  • external radiotherapy with chemotherapy and then more chemotherapy

  • chemotherapy followed by radiotherapy

  • chemotherapy on its own

Some people may have treatment with immunotherapy or a targeted cancer drug. This will depend on your situation and whether you’ve had other treatments before. Possible treatments include:

  • immunotherapy with chemotherapy

  • immunotherapy on its own

  • immunotherapy and a targeted cancer drug

You doctor may recommend you have chemotherapy to try to slow the growth of the cancer and to relieve symptoms.

Read about immunotherapy and targeted therapy

Other treatments

You will also have other more specific treatments that help with any symptoms you have. This might include pain killers for pain or medicines for sickness. 

There might be trials of experimental treatments which you could take part in. These might be looking at:

  • new treatments

  • ways to improve existing treatments such as radiotherapy or chemotherapy and when you have them

You can search our clinical trials database for womb cancer trials.

Find out more about clinical trials

Other stages

Last reviewed: 27 Mar 2024

Next review due: 27 Mar 2027

Stages of womb cancer

The stage of a cancer tells you how big it is and whether it has spread. This helps your doctor decide which treatment you need.

Types and grades of womb cancer

The type of womb cancer you have depends on the type of cell the cancer started in. The grade gives doctors an idea of how fast growing the cancer is.

Treatment for womb cancer

Your treatment depends on several factors. These include what type of womb cancer you have, how big it is, whether it has spread (the stage) and the grade. It also depends on your general health.

Living with womb cancer

There is support available during and after treatment to help you cope. This includes support from your clinical nurse specialist, cancer charities, community services, and family and friends.

Survival for womb cancer

Survival depends on many factors including the stage and grade of your womb cancer.

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