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Treatment for penile cancer

Other treatments for penile cancer

Your doctor may recommend treatment with lasers or creams for very early penile cancer, or penile intraepithelial neoplasia (PeIN).

Laser treatment

Your surgeon uses a powerful beam of light that acts like a knife. It cuts away the cancer cells but doesn't go too deep into the tissue. You have a local or general anaesthetic. If you have a general anaesthetic you are asleep for the whole operation.

Read more about laser treatment

Chemotherapy cream

Chemotherapy cream only kills the cancer cells in the area of skin treated. Doctors use it for PeIN, or small early stage cancer on the foreskin or end of the penis. It is called topical chemotherapy.

You usually have your foreskin removed (circumcision) before you have topical creams.

The chemotherapy drug in the cream is fluorouracil (5FU). Or it could be a cream called imiquimod. Imiquimod uses the immune system to fight cancer.

You put the cream on the cancerous area, every day for several weeks. The cream only kills cancer cells in the top layers of the skin. It doesn't treat deeper cancers.

Side effects

Your skin might become sore, red and inflamed when using chemotherapy cream. Tell your doctor or nurse if this happens. They can give you other creams and painkillers to help. These side effects should wear off within a couple of weeks after stopping treatment.

You don't lose your hair with chemotherapy creams.

Get more information on imiquimod cream (Aldara)

Last reviewed: 28 Feb 2024

Next review due: 28 Feb 2027

Treatment for penile cancer

Treatments for penile cancer include surgery, chemotherapy and radiotherapy. The treatment you have depends on the stage and type of your penile cancer.

Stages, types and grades of penile cancer

The stage, type and grade of your cancer helps your doctor decide which treatment you need.

Follow up after penile cancer treatment

At first, you usually have follow up appointments every few months to check how you are.

Living with penile cancer

Coping with penile cancer can be difficult. There are things you can do, people who can help and ways to cope with your diagnosis.

Penile cancer main page

Penile cancer is cancer of the penis. It can develop anywhere on the penis but is most common under the foreskin in men who haven’t been circumcised or on the head of the penis (the glans).

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