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Nasopharyngeal cancer

What is nasopharyngeal cancer?

Nasopharyngeal cancer is when abnormal cells in the nasopharynx start to divide and grow in an uncontrolled way. The cells can grow into surrounding tissues and may spread to other areas of the body.

The nasopharynx

The nasopharynx is the top part of the pharynx (throat). It connects the back of your nose to the back of your mouth. Cancer that develops in the nasopharynx is called nasopharyngeal cancer. Nasopharyngeal is pronounced nas-o-fa-rin-jee-al.

You can’t see your own nasopharynx directly. It lies above the soft area at the back of the roof of your mouth (your soft palate) and the dangly part (uvula) at the back of your mouth. You might see these if you look inside your mouth using a mirror.

Parts of the pharynx (throat)

The pharynx is in 3 parts:

  • the area at the back of the nose (nasopharynx)

  • the part of the throat at the back of the mouth - the medical term is oropharynx

  • the area that sits behind and on either side of the ​​ - called the hypopharynx

Diagram showing the parts of the pharynx .

What throat cancer means

Throat cancer is not an exact medical term, so doctors do not generally use it. Many people use the term throat cancer to mean cancer that has developed in any of the 3 parts of the pharynx. They might also use it to mean cancers near the pharynx, such as cancer of the:

  • voice box (larynx)

  • food pipe (oesophagus)

It is important to know the exact medical name of the cancer you have, so you can find the right information.

Cancers are treated according to where they started. For example, the treatment for thyroid cancer is different to the treatment for nasopharyngeal cancer. If you are not sure of the medical name of your cancer, ask your doctor or nurse to write it down for you.

Read more about what throat cancer can mean

Read about other cancer types

Where does nasopharyngeal cancer start?

Nasopharyngeal cancer starts in the lining of the nasopharynx. It may spread to lymph nodes or other parts of the body, such as the lungs or bones.

The most common type of nasopharyngeal cancer is keratinizing squamous cell carcinoma.

Squamous cells are the flat, skin-like cells that cover the lining of the mouth, nose, voice box (larynx), thyroid and throat. Carcinoma means cancer. So, squamous cell carcinoma is a cancer that starts in these cells.

Other types include

  • nonkeratinizing carcinoma 

  • basaloid squamous cell carcinoma 

Read more about the types of nasopharyngeal cancer

Lymph nodes in your neck

Like other parts of the body, the neck contains lymph nodes (also called lymph glands).

These small, bean shaped glands are part of the lymphatic system which runs throughout the body. Lymph nodes filter the lymph fluid as it passes through them. They can trap bacteria, viruses and cancer cells.

Lymph nodes are often the first place cancer cells spread to when they break away from a cancer. There are groups of lymph nodes in the neck. If you have nasopharyngeal cancer, it might spread to these lymph nodes.

Diagram showing the lymph nodes in the head and neck.

Read more about the lymphatic system and cancer

How common is nasopharyngeal cancer?

Nasopharyngeal cancer is a rare cancer. Around 260 people are diagnosed with nasopharyngeal cancer in the UK every year. It is more common in men than women.  

Read about the risk factors for nasopharyngeal cancer

Last reviewed: 07 May 2024

Next review due: 07 May 2027

Risks and causes of nasopharyngeal cancer

Anything that can increase your risk of getting a disease is called a risk factor. Nasopharyngeal cancer is rare in the UK. Smoking certain substances and a history of Epstein-Barr virus (EBV) are examples of the risks and causes of nasopharyngeal cancer.

Symptoms of nasopharyngeal cancer

Nasopharyngeal cancer can cause symptoms. For example, nose and ear problems, as well as other symptoms such as a lump in the neck.

Getting diagnosed with nasopharyngeal cancer

You see your GP if you have symptoms. They can refer you for tests or to see a specialist. One of the tests you might have is a nasendoscopy, which looks at the inside of your nose, throat and voice box.

Treatment for nasopharyngeal cancer

You usually have radiotherapy as part of your treatment for nasopharyngeal cancer. You might also have other treatments, such as chemotherapy.

Survival for nasopharyngeal cancer

Survival depends on many factors so you can only use these figures as a guide. Your doctor can give you information about your own outlook (prognosis).

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