Surgery for liver cancer
A complication is anything that happens after surgery that makes your recovery more difficult. Before offering surgery as an option to you, your doctors make sure the benefit of having the operation outweighs the possible risks.
Your doctors will talk to you about the possible complications of the surgery and general anaesthetic. They will do this before you sign the consent form to have the operation. Your doctors and nurses monitor you very closely to check for problems. Even when you go home, they will see you regularly to make sure you are recovering well.
Some complications can be serious. But they are becoming less common as surgeons get better at deciding who is likely to make a good recovery.
There is a risk of infection after an operation. The wound area might be red and sore. If you have a chest infection you might have a cough or feel short of breath. You might also feel generally unwell and have a temperature.
Let your doctor or nurse know if you have any symptoms. They can give you antibiotics through a drip or as tablets.
After any operation there is a risk of bleeding. This is particularly the case with liver surgery as a lot of blood passes through the liver. Also, your liver normally makes substances that help your blood to clot. So any damage to the liver can cause problems with bleeding.
Your doctors and nurses will monitor you closely during and after the operation. They will check for possible signs of bleeding. You may need a blood transfusion after your operation. Rarely you may need to go back to theatre for another operation to stop the bleeding.
Bile is a fluid that helps to digest food by breaking down fat. The liver makes bile which is stored in the gallbladder. Small tubes called bile ducts carry the bile into the small bowel. The bile ducts connect the liver and gallbladder to the small bowel.
There is a risk of bile leaking from the ducts on the cut surface of the liver. This may cause pain, sickness and a high temperature. Rarely, you might need another operation to repair the leak.
There is a risk that your kidneys may stop working properly after the operation. Your doctors and nurses will keep a close eye on blood test results and how much urine you make. Your kidneys usually recover over time. But some people require kidney support (dialysis) after major surgery.
You might have a build up of fluid in your tummy (abdomen) called ascites.
This can happen for different reasons, including an increase in pressure in one of the main blood vessels of the liver (portal vein). Your doctor can give you medicines to help reduce the fluid. Or in some situations, they may put in a tube into your tummy to drain the fluid.
Read more about ascites and its treatment
Blood clots (deep vein thrombosis, DVT) are a possible complication of having surgery. This is because you might not move about as much as usual. Clots can block the normal flow of blood through the body. Let your doctor or nurse know if you have an area in your leg that is swollen, hot, red or sore.
There is a risk that a blood clot can become loose and travel through the bloodstream to the lungs. This causes a blockage in the lung called a pulmonary embolism. Symptoms include:
shortness of breath
chest pain
coughing up blood
feeling dizzy or lightheaded
To try to prevent blood clots you wear compression stockings after surgery. You also have daily injections for several weeks to thin your blood. And your nurses will encourage you to get up as soon as possible or do regular leg exercises.
Read more about blood clots and its treatment
Although uncommon, there is a risk of a blood clot developing in one of the main blood vessels to and from the liver. These are the hepatic artery, portal vein or hepatic veins. You may have drugs to thin the blood if this happens. In some cases, you may need another operation.
There is a risk that your remaining liver doesn’t work after your operation. This is a rare but serious complication and can be life threatening.
This page is due for review. We will update this as soon as possible.
Last reviewed: 25 Nov 2021
Next review due: 25 Nov 2024
Find out what to expect immediately after surgery and when you go home.
A liver transplant is an operation to remove your liver and replace it with a healthy liver from a donor.
Your treatment for liver cancer depends on the stage of your cancer and how well your liver is working. The most common treatments are surgery, heat treatment, drug treatments and radiotherapy.
Coping with cancer can be difficult. Help and support are available. There are things you can do, people to help and ways to cope with a diagnosis of liver cancer.
After treatment for liver cancer you have regular follow up appointments and might need to have some tests.
Primary liver cancer is cancer that started in the liver. This section is mainly about the most common type of liver cancer, hepatocellular carcinoma (HCC).

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