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Hairy cell leukaemia

Risks and causes of hairy cell leukaemia

We don't know what causes hairy cell leukaemia. But there are some factors that may increase your risk of developing it. Having one or more of them doesn't mean that you will definitely get leukaemia.

What is a risk factor?

Anything that can increase your risk of getting a disease is called a risk factor. Different cancers have different risk factors. Having one or more of these risk factors doesn't mean you will definitely get that cancer.

Risk factors for hairy cell leukaemia

Your risk of developing cancer depends on many factors. This includes things like whether you smoke and have a healthy balanced diet. And also genetic and environmental factors.

Risk factors for hairy cell leukaemia include:

Age

Hairy cell leukaemia is rarely diagnosed in adults under the age of 30. It is hardly ever diagnosed in children.

Gender

Hairy cell leukaemia is more common in men than women. About 4 times as many men are diagnosed than women. 

Ethnicity

Hairy cell leukaemia is seen more often in White people compared with Black and Asian people. 

Family history

Your risk is slightly higher if you have a close relative (parent, sibling, child) diagnosed with hairy cell leukaemia. But most people with a family history of hairy cell leukaemia do not develop it themselves and the risk remains very low.

Other possible causes

There are often stories about potential causes in the media. It isn’t always clear which ideas are supported by evidence. There might be things you have heard of that we haven’t included here. This is because either there is no evidence about them or it is less clear.

Find out more about controversies and cancer

Last reviewed: 14 Oct 2024

Next review due: 14 Oct 2027

Diagnosing hairy cell leukaemia

You usually start by seeing your GP and they might refer you to a specialist and organise tests. Find out more about tests and screening for hairy cell leukaemia.

Stages of hairy cell leukaemia

The stage means how far your leukaemia has developed. There is no widely agreed staging system for hairy cell leukaemia.

Treatment for hairy cell leukaemia

There are different treatments for hairy cell leukaemia. You might have one treatment, or a combination. The main treatment is chemotherapy.

Survival for hairy cell leukaemia

Hairy cell leukaemia usually develops slowly and can be kept under control for many years with treatment.

Research and clinical trials for hairy cell leukaemia

Researchers around the world are looking into the causes and treatment of hairy cell leukaemia.

Hairy cell leukaemia main page

Hairy cell leukaemia (HCL) is a rare type of chronic leukaemia. It develops slowly from white blood cells called B lymphocytes. Find out about this type of leukaemia.

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