Lung cancer, Non small cell lung cancer (NSCLC), Secondary cancers
Open
Phase 3
This trial is comparing MK-3475A and calderasib with MK-3475A and .
It is open to people who:
have a type of non small cell lung cancer called non squamous cell
are having their first treatment for lung cancer that has spread
have a gene change () called KRAS G12C in their lung cancer cells
You pronounce calderasib as kal-dair-ah-sib.
Recruitment start: 13 April 2026
Recruitment end: 7 August 2028
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Dr Ekaterini Boleti
Merck Sharp & Dohme Ltd
Last reviewed: 21 May 2026
CRUK internal database number: 20159