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Causes of fever

Does cancer cause fever?

Some cancers can cause fevers. It's not fully understood why some cancers cause fevers and others don't.

Cancers that cause fever

It's thought that some cancers may produce proteins called that can cause a fever.

The cancers most likely to cause fevers include:

  • non-Hodgkin lymphoma (NHL)

  • Hodgkin lymphoma

  • acute or chronic leukaemia

  • kidney cancer (renal cell cancer)

  • liver cancer (hepatocellular carcinoma)

  • soft tissue sarcoma - this is cancer of the supporting tissues of the body such as the muscle, nerves, fat and blood vessels

  • adrenal gland tumours such as phaeochromocytomas

  • tumours in the part of the brain called the hypothalamus such as chordoid glioma

  • ovarian cancer

Your doctors might not be able to find any reason for your fever.

Some types of Hodgkin lymphoma and non-Hodgkin lymphoma cause night sweats and high temperatures that come and go with no obvious cause. This symptom, along with other tests can help diagnose what type of cancer you have. 

Rarely, some people with Hodgkin lymphoma might have a fever in cycles. This means your temperature rises and falls over a week or two. You may have days or weeks when you don't have a temperature and then the fever starts again.

Cancers that don't often cause fever

The most common types of cancer, such as breast cancer, lung cancer and bowel cancer, do not generally cause fever. But they may do if:

  • the cancer has spread to the liver

  • the cancer is causing an obstruction or blockage somewhere in your body

Treating fever

There are a number of treatments available to help you with a fever.

Find out about treating fever

Last reviewed: 24 Mar 2026

Next review due: 23 Mar 2029

Other causes of fever

Apart from your cancer treatment, there are a number of other reasons why you might get a fever when you have cancer.

Treating fever and infection

Treatment for a fever will depend on what's causing it. As well as treating the cause of your fever, you need treatment for your fever symptoms.

Treating the cause of your fever

Treatment for a fever will depend on what is causing it.

Sepsis, infection and cancer

Sepsis is a serious complication of an infection that can be life threatening. Fever might be the first sign of an infection, or you might have other symptoms.

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