Dukes' staging system

Doctors use different systems for staging bowel cancer. The most common system for bowel cancer is TNM staging.

The Dukes' staging system is not really used anymore. But you might hear your doctor talking about your bowel cancer as Dukes’ A,B,C or D.

Dukes' A

The cancer is in the inner lining of the bowel. Or it is slightly growing into the muscle layer.  

Diagram showing Dukes' A bowel cancer

Dukes' B

The cancer has grown through the muscle layer of the bowel. 

Diagram showing Dukes' B bowel cancer

Dukes' C

The cancer has spread to at least 1 lymph node Open a glossary item close to the bowel. 

Diagram showing Dukes' C bowel cancer

Dukes' D

The cancer has spread to another part of the body, such as the liver, lungs or bones. 

In the number staging system, this is the same as stage 4. It is also called metastatic or advanced bowel cancer.

Diagram showing Dukes' D bowel cancer

Treatment

The stage of your cancer helps your doctor to decide which treatment you need. Treatment also depends on:

  • your type of cancer (the type of cells the cancer started in)
  • where the cancer is in your bowel (colon or rectum)
  • other health conditions that you have

The stage of the cancer and these other factors can also give an idea of your outlook (prognosis).

The main treatments for cancer of the large bowel (colon cancer) are:

  • surgery
  • chemotherapy Open a glossary item

The main treatments for cancer of the back passage (rectal cancer) are:

  • surgery
  • radiotherapy Open a glossary item
  • chemotherapy
  • chemotherapy and radiotherapy together (chemoradiotherapy Open a glossary item)

Metastatic cancer means your cancer has spread away from where it started. It is also called advanced cancer.

You might have chemotherapy or radiotherapy for bowel cancer that has spread. Sometimes you can also have surgery. This is to remove as much cancer as possible and help with your symptoms.

 You might also have:

•    a targeted cancer drug Open a glossary item 
•    immunotherapy  Open a glossary item

Other staging systems

  • Colorectal cancer
    National Institute for Health and Care Excellence, January 2020. Last updated 15 December 2021

  • Rectal cancer: ESMO clinical practical guidelines for diagnosis, treatment and follow up
    R Glynne-Jones and others
    Annals of Oncology, 2017. Volume 28, Supplement 4

  • Association of Coloproctology of Great Britain & Ireland (ACPGBI): Guidelines for the management of cancer of the colon, rectum and anus (2017) – diagnosis, investigations and screening 
    C Cunnigham and others  
    Colorectal disease, 2017. Volume 19, Pages 1-97

  • Metastatic colorectal cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up

    A Cervantes and others

    Annals of oncology, 2022. Volume 34, Issue 1

  • Clinical Oncology, Basic Principles and Practice (5th Edition)

    Peter Hoskin

    CRC Press, 2020

  • The Dukes staging system: a cornerstone in the clinical management of colorectal cancer

    A Haq and others

    The Lancet Oncology, 2009. Volume 10, Issue 11

Last reviewed: 
07 Nov 2024
Next review due: 
07 Nov 2027

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