Graeme sits in a garden looking happy.

Annual supporter update 2025/26

With your support, we spent £416m on new and ongoing research this year. That’s not just a big number – it's the fuel that’s powering breakthroughs.

Life-saving breakthroughs, thanks to you

We’ve gathered some of our most exciting updates from the past 12 months so you can see the big strides we’re making towards beating cancer – all thanks to you.  

Discover how we're: 

  • launching a world-first clinical trial of a vaccine aiming to prevent lung cancer in people at high risk

  • making bowel cancer cells self-destruct

  • using tears to detect brain tumours 

  • helping to create the UK’s first smokefree generation

  • uncovering a weakness in pancreatic cancer 

And so much more! You’ll also hear from people like Graeme, pictured above, who’ve shared their own experiences to show how your support is helping to shape a better future for people affected by cancer. 

Read your annual update

Thank you from our chief executive 

Michelle Mitchell shares a heartfelt thanks in this short video.

Outnumbering cancer together

A photo of two Race for Life supporters after their race.

240,107

of you went All In at Race for Life, raising £36.4m across 476 events in 2025.

A photo of three Cancer Research UK Campaigns Ambassadors.

2.3 million

hours of time were given by our incredible shop volunteers, who served happy customers to support cutting-edge science. 

Two researchers in a lab looking at samples.

£62m

was raised by our passionate community of monthly donors, helping us commit to complex, long-term projects with huge potential to change lives. 

A woman sitting at a table with a lawyer, smiling as they review the document.

8,600

of you pledged a generous gift in your Will to help back tomorrow’s breakthroughs. 

Read your annual update

Accessible version

We want everyone to access this update in a way that works for them. It’s also available as an accessible PDF. 

View PDF version

A photo of a researcher in a lab.

Read our full annual report

Get more detailed information on how we spend your money and the progress we’ve made together over the last year. 

Meet Graeme

Graeme, a patient and public involvement representative, sits at a bench in the countryside, he is smiling.

Thanks to science, I’ve been able to enjoy many more happy years with my family since my lung cancer diagnosis in 2013. Now, I’m helping scientists prepare for a world-first clinical trial.

- Graeme, 55, from Renfrewshire in Scotland

Making history together

Campaigns Ambassadors holding a banner that reads MPs, help end cancers caused by smoking.

On 29 April 2026, the Tobacco and Vapes Act officially became law in the UK. This world-leading legislation will prevent people born on or after 1 January 2009 from ever being legally sold tobacco in the UK, helping to create our first smokefree generation. 

Your voices also helped us campaign for...

A Cancer Research UK campaigner holding up a sign that says together we will beat cancer in Welsh.

a Turning point for cancer in Scotland and Wales

We urged the incoming governments in both nations to take action on cutting cancer waiting times, increasing early diagnosis and investing more in research. 

Two Cancer Research UK campaigners distribute leaflets with the House of Commons in the background.

a National Cancer Plan that’s bold and fully funded

More than 35,000 of you signed our open letter to the health secretary and we’ll keep holding politicians to account to make sure people affected by cancer get the research and care they deserve. 

Thanks to you, we're…

Illustration of lots of cells including a self-destructing cell.

making bowel cancer cells self-destruct

Cancer Grand Challenges team REWIRE-CAN is pioneering a bold new approach to bowel cancer treatment.

Instead of blocking the signals that drive tumour growth, they aim to amplify them, causing cancer cells to self-destruct. 

Illustration of a woman with tears on her face alongside a vial containing tears.

using tears to detect brain tumours

In Manchester, our scientists are developing a test to detect signs of brain tumours in tears.

Their goal is to give doctors a tool to help spot tumours and diagnose people sooner, when treatment is more likely to be successful.

Illustration of a man with a circle on his lower body highlighting his pancreas.

uncovering a weakness in pancreatic cancer

At the Cancer Research UK Scotland Centre, our researchers have uncovered curious dementia-like behaviour in cells during the development of pancreatic cancer.

This curious discovery could give us vital clues on how pancreatic cancer develops and unlock new ways to prevent, detect and treat it.

Read your annual update

Be part of our progress