Brain, other CNS and intracranial tumours are the eighth most common cancer in the UK (2013), accounting for 3% of all new cases. They are the 10 most common cancers in males (3% of all male cases) and the eighth most common in females (3% of all female cases).[1-4]
In 2013, 10,624 new brain, other CNS and intracranial tumour cases were registered in the UK 5,164 (49%) in males and 5,460 (51%) in females, giving a male:female ratio of around 9:10.[1-4] The crude incidence rate shows that there are 16 new brain, other CNS and intracranial tumour cases for every 100,000 males in the UK and 17 for every 100,000 females.[1-4]
Brain, Other CNS and Intracranial Tumours (C70-C72, C75.1-C75.3, D32-D33, D35.2-D35.4, D42-D43, D44.3-D44.5), Number of New Cases, Crude and European Age-Standardised (AS) Incidence Rates per 100,000 Population, UK, 2013
|AS Rate - 95% LCL||17.7||19.3||18.0||7.7||17.8|
|AS Rate - 95% UCL||18.8||24.1||21.6||12.1||18.8|
|AS Rate - 95% LCL||16.4||21.6||17.3||5.9||16.7|
|AS Rate - 95% UCL||17.4||26.4||20.5||9.7||17.6|
|AS Rate - 95% LCL||17.2||21.3||18.1||7.4||17.4|
|AS Rate - 95% UCL||17.9||24.7||20.5||10.3||18.0|
95% LCL and 95% UCL are the 95% lower and upper
ASR calculated with ESP2013. Not comparable with ASRs calculated with ESP1976.
Under-recording of brain, other CNS and intracranial tumours by cancer registries is possible, though there are presently no reliable data on the extent of this. Two small studies in the 1990s estimated that around 50% of brain, other CNS and intracranial tumours went unrecorded in UK cancer registries;[5,6] however, the situation is now thought to have improved.[7,8] Fatal and/or heavily-treated cases are more likely to be captured by cancer registries (because data on these cases appear in multiple systems to which the registries have access, including death records). Thus, it is likely that non-fatal or conservatively-treated cases represent the majority of any unrecorded tumours. The National Brain Tumour Registry for England has been set up to provide more detailed and consistent information in the future.[8,9]
- Data were provided by the Office for National Statistics on request, July 2015. Similar data can be found here: http://www.ons.gov.uk/ons/search/index.html?newquery=cancer+registrations
- Data were provided by ISD Scotland on request, April 2015. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications/index.asp
- Data were provided by the Welsh Cancer Intelligence and Surveillance Unit on request, February 2015. Similar data can be found here: http://www.wcisu.wales.nhs.uk/officical-statistics-exel-files-of-trend
- Data were provided by the Northern Ireland Cancer Registry on request, March 2015. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/
- Pobereskin L. The Completeness Of Brain Tumour Registration In Devon And Cornwall. Eur J Epidemiol 2001;17(5):413-416.
- Counsell C, Collie D, Grant R. Limitations of using a cancer registry to identify incident primary intracranial tumours. J Neurol Neurosurg Psychiatry 1997;63:94-97.
- Eastern Cancer Registry and Information Centre (ECRIC), National Brain Tumour Registry. Personal communication, February 2013.
- Data were provided by UK Cancer Registry representatives on request, 2008.
- National Cancer Intelligence Unit (NCIN). Central Nervous System (CNS) Tumours â developing a national tumour registry. London: NCIN; 2011.