Clinical Research Committee

The Clinical Research Committee oversees funding and endorsement of investigator-led clinical trials, and other research supporting or enabling clinical trials.

The priorities of the CRC are set out in our statement of intent and build on those established in the CRUK Research Strategy.

The CRC is a successor to the former Clinical Trials Awards and Advisory Committee (CTAAC) and the Feasibility Study Committee (FSC).

Research areas

CRC maintains a broad portfolio that maximises patient impact. We support a balance of research across the range of modalities and disease sites, conducted in early, pre-invasive, localised disease and metastatic settings.

Our investment priorities include:

  • Cancers of unmet need (lung, oesophageal, pancreatic and brain cancers)
  • Promising, high impact and innovative trials that would not otherwise progress
  • Scientifically-driven studies that use and analyse biomarkers and imaging, producing valuable biological and clinical information that will optimise treatments
  • Hypothesis-driven, data-rich sample collections that support the validation and qualification of valuable biological information
  • Innovative, cost-effective trial designs that can be supported by strategic long-term investments in trial platforms

Funding schemes

In line with our statement of intent, we have also reviewed and updated the remits of the funding schemes that sit with CRC. We have moved from cost caps to guide costs, and we have added a new experimental medicine scheme to support more biologically rich clinical research. You can find full details in our FAQs and as always, contact the team if you want to discuss the fit of your proposal within these schemes.

CRC reviews, funds and endorses:

How proposals are judged

The Committee and its Expert Review Panels meet twice a year and assess all applications on the basis of their scientific quality, taking into consideration comments collected from expert peer reviewers. The Committee strategically assess applications based on their alignment to the Statement of Intent for Clinical Research (PDF), and our Research Strategy.

Read terms of reference for this committee

How grants are monitored

Grants are monitored through the Clinical Research Monitoring Panel (CRMP). The Panel meets twice a year to review annual Scientific Milestone Reports and determine whether to continue support.

Read the terms of reference for the CRMP

​Chair of the Clinical Research Committee

Chair Professor Tim Maughan - University of Oxford

Vice Chairs of the Clinical Research Committee

Professor Caroline Dive - University of Manchester

Dr James Larkin - The Institute of Cancer Research/The Royal Marsden

Members of the Clinical Research Committee

Professor Richard Adams - Cardiff University

Dr Jan Bogaerts - EORTC

Professor David Cameron - University of Edinburgh

Professor Johann De Bono - The Institute of Cancer Research/The Royal Marsden

Dr Ferdia Gallagher - University of Cambridge

Professor Paula Ghaneh - University of Liverpool

Professor Richard Gilbertson - University Cambridge

Professor Kevin Harrington - The Institute of Cancer Research/The Royal Marsden

Professor Andrew Hughes - University of Manchester

Professor Gary Middleton - University of Birmingham

Professor Mark Middleton - University of Oxford

Professor Max Parmar - University College London

Mr Jim Paul - University of Glasgow

Professor Ruth Plummer - University of Newcastle

Mr John Reeve - Patient Representative

Mr Richard Stephens - Patient Representative

Professor Charles Swanton - University College London/Francis Crick Institute

Chair of the Clinical Expert Review Panel

Professor David Cameron - University of Edinburgh

Vice Chair of the Clinical Expert Review Panel

Professor Richard Adams - University of Birmingham

Members of the Clinical Expert Review Panel

Professor Lucinda Billingham - University of Birmingham

Professor Neil Burnet - University of Cambridge

Mr David Chuter - Patient Representative

Dr Helena Earl - University of Cambridge

Professor Jeff Evans - University of Glasgow

Professor Corinne Faivre-Finn - University of Manchester

Dr Eve Gallop-Evans - Cardiff University

Dr Darren Hargrave - Great Ormond Street/University College London

Mr Chris Hurt - Cardiff University

Dr Muriel Mauer - EORTC

Professor Alex Mirnezami - University of Southampton

Dr Marianne Nicolson - Aberdeen Royal Infirmary

Dr Karin Oien - University of Glasgow

Professor Max Parmar - University College London

Dr Sanjay Popat - The Institute of Cancer Research/The Royal Marsden

Mr Richard Stephens - Patient Representative

Professor Josef Vormoor - University of Newcastle

Professor Richard Wilson - Queen's University Belfast

​Chair of the Experimental Medicine Expert Review Panel

Professor Charles Swanton - University College London/Francis Crick Institute

Vice Chair of the Experimental Medicine Expert Review Panel

Professor Mark Middleton - University of Oxford

Members of the Experimental Medicine Expert Review Panel

Professor Fabrice Andre - Institute Gustave-Roussy

Mrs Sylvia Bailey - Patient Representative

Dr Sarah Brown - University of Leeds

Dr Francesca Buffa - University of Oxford

Dr Simon Crabb - University of Southampton

Dr Emma Dean - University of Manchester

Professor Malcolm Dunlop - University of Edinburgh

Dr Adele Fielding - University College London

Professor Rebecca Fitzgerald - University of Cambridge

Professor Charlie Gourley - University of Edinburgh

Professor Allan Hackshaw - University College London

Professor Kevin Harrington - The Institute of Cancer Research/The Royal Marsden

Dr Geoff Higgins - University of Oxford

Professor Jason Lewis - Memorial Sloan Kettering Cancer Center

Professor Gary Middleton - University of Birmingham

Professor Peter Parker - King's College London/Francis Crick Institute

Professor Tom Powles - Queen Mary, University of London

Mr John Reeve - Patient Representative

Professor Manuel Salto-Tellez - Queen's University Belfast

Ms Louise Stanton - University of Southampton

Professor Gareth Thomas - University of Southampton

Professor Andrew Tutt - King's College London/The Institute of Cancer Research

Chair of the Clinical Research Monitoring Panel

Dr James Larkin – The Institute of Cancer Research/The Royal Marsden

Vice Chair of the Clinical Research Monitoring Panel

Professor Paula Ghaneh – University of Liverpool

Members of the Clinical Research Monitoring Panel

Professor Gordon Cook – University of Leeds

Professor Peter Johnson – University of Southampton

Mr Jim Paul – University of Glasgow

Mr John Reeve – Patient Representative

Mr Matthew Sydes – University College London

Contact for this committee

Caroline Dalton

Dr Caroline Dalton

​Senior Research Funding Manager

clinicalresearch@cancer.org.uk

Tel: +44 (0) 20 3469 8860

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