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Uterine cancer survival statistics

One-, five- and ten-year survival statistics for uterine cancer by age and trends over time are presented here. There are also data by stage at diagnosis, geography and on socio-economic variation.

Find out more about the counting and coding of this data.

 

One-, five- and ten-year survival

90% of women survive uterine cancer for at least one year, and this is predicted to fall to 79% surviving for five years or more, as shown by age-standardised net survival for patients diagnosed with uterine cancer during 2010-2011 in England and Wales (Table 3.1).1

Table 3.1: Uterine Cancer (C54-C55), Age-Standardised One-, Five- and Ten-Year Net Survival, Women (Aged 15-99), England and Wales, 2010-2011

1-Year Survival (%) 5-Year Survival (%) 10-Year Survival (%)
Women Net Survival 90.3 79.0 77.5
95% LCL 90.3 79.0 77.4
95% UCL 90.3 79.0 77.6

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95% LCL and 95% UCL are the 95% lower and upper confidence limits
Five- and ten-year survival is predicted using an excess hazard statistical model

Uterine cancer survival falls only slightly beyond five years after diagnosis, which means most patients can be considered cured after five years. 78% of women are predicted to survive their disease for ten years or more, as shown by age-standardised net survival for patients diagnosed with uterine cancer during 2010-2011 in England and Wales (Figure 3.1).1 Out of 20 common cancers in England and Wales, ten-year survival for uterine cancer ranks 6th highest overall (and 4th highest for females only).

Figure 3.1: Uterine Cancer (C54-C55), Net Survival up to Ten Years after Diagnosis, Women (Aged 15-99), England and Wales, 2010-2011

surv_curve_uterus2.swf

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Survival for uterine cancer is reported in Scotland and Northern Ireland,2,3 though it is difficult to make survival comparisons between countries due to different methodologies and criteria for including patients in analyses.

section reviewed 10/12/14
section updated 10/12/14

 

By age

Five-year survival for uterine cancer is highest in the youngest women and generally decreases with increasing age. Five-year net survival ranges from 88% in 15-39 year-olds to 56% in 80-99 year-olds for patients diagnosed with uterine cancer in England during 2007-2011 (Figure 3.2).4

Figure 3.2: Uterine Cancer (C54-C55), Five-Year Net Survival by Age, England, 2007-2011

surv_5yr_age_uterus.swf

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section reviewed 10/12/14
section updated 10/12/14

 

Trends over time

As with most cancers, survival for uterine cancer is improving. One-year age-standardised net survival has increased from 75% during 1971-1972 to 90% during 2010-2011 in England and Wales – an absolute survival difference of 15 percentage points (Figure 3.3).1

Figure 3.3: Uterine Cancer (C54-C55), Age-Standardised One-Year Net Survival, Women (Aged 15-99), England and Wales, 1971-2011

surv_1yr_uterus.swf

Download this chart XLS (46KB) PPT (127KB) PDF (44KB)

Five- and ten-year survival has increased by an even greater amount than one-year survival since the early 1970s. Five-year age-standardised net survival for uterine cancer has increased from 59% during 1971-1972 to a predicted survival of 79% during 2010-2011 in England and Wales – an absolute survival difference of 20 percentage points (Figure 3.4).1

Figure 3.4: Uterine Cancer (C54-C55), Age-Standardised Five-Year Net Survival, Women (Aged 15-99), England and Wales, 1971-2011

surv_5yr_uterus.swf

Download this chart XLS (45KB) PPT (127KB) PDF (44KB)

Five-year survival for 2010-2011 is predicted using an excess hazard statistical model

Ten-year age-standardised net survival for uterine cancer has increased from 55% during 1971-1972 to a predicted survival of 78% during 2010-2011 in England and Wales – an absolute survival difference of 22 percentage points (Figure 3.5).1 Overall, more than three-quarters of women diagnosed with uterine cancer today are predicted to survive their disease for at least ten years.

Figure 3.5: Uterine Cancer (C54-C55), Age-Standardised Ten-Year Net Survival, Women (Aged 15-99), England and Wales, 1971-2011

surv_10yr_uterus.swf

Download this chart XLS (45KB) PPT (126KB) PDF (44KB)

Ten-year survival for 2005-2006 and 2010-2011 is predicted using an excess hazard statistical model

section reviewed 10/12/14
section updated 10/12/14

 

By stage at diagnosis

Survival for uterine cancer is related to stage of the disease at diagnosis. The majority of patients are diagnosed at Stages I or II.

One-year relative survival for uterine cancer (cancer of the body of the uterus only [C54]) is highest at Stages I and II, with 98% and 94% of patients, respectively, surviving their disease for at least one year for patients diagnosed during 2006-2010 in the former Anglia Cancer Network (Figure 3.6).5 One-year survival is lowest for those diagnosed with Stage IV disease (35%). As very few patients are diagnosed at Stages III or IV, the one-year survival statistics have wide confidence limits and should therefore be interpreted with caution.

Figure 3.6 Cancer of the Body of the Uterus (C54), One-Year Relative Survival by Stage, Women (Aged 15-99 Years), Former Anglia Cancer Network, 2006-2010

surv_1yr_stage_w_uterus.swf

Download this chart XLS (46KB) PPT (128KB) PDF (48KB)

Five-year survival for uterine cancer shows a much more rapid decrease in survival between Stages I and IV. Five-year relative survival ranges from 95% at Stage I to 14% at Stage IV for patients diagnosed during 2002-2006 in the former Anglia Cancer Network (Figure 3.7).5

Figure 3.7 Cancer of the Body of the Uterus (C54), Five-Year Relative Survival by Stage, Women (Aged 15-99 Years), Former Anglia Cancer Network, 2002-2006

surv_5yr_stage_w_uterus.swf

Download this chart XLS (46KB) PPT (128KB) PDF (48KB)

section reviewed 10/12/14
section updated 10/12/14

 

In Europe and worldwide

One-year survival for women in England diagnosed with uterine cancer (C54 only) in 1995-99 was significantly below the European average (88%).6 Five-year relative survival was also lower (75%) but not significantly lower than the European average. Women in the United States diagnosed with uterine cancer (C54 only) in 1995-2001 had five-year survival of 85%.7

In the United States there are significant differences in survival between African American and white women.7 While this could partly be due to differences in treatment between the two groups, African American women are significantly more likely to get high-grade tumours and to present at a later stage.8

section reviewed 22/06/12
section updated 22/06/12

 

By socio-economic variation

For women diagnosed in 1996-1999 there is a significant gap in five-year survival between the most deprived and least deprived women of 4.5%.9 Regional differences in survival reflect this deprivation gradient. Wales had the lowest relative one and five-year survival for women diagnosed in 1986-90, while the South and West regions in England had the highest.10

section reviewed 22/06/12
section updated 22/06/12

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References for uterine (womb) cancer survival

  1. Cancer Research UK Cancer Survival Group, London School of Hygiene and Tropical Medicine. Personal communication, 2014.
  2. ISD Scotland. Trends in Cancer Survival 1983-2007.
  3. Northern Ireland Cancer Registry. Incidence & Survival 1993-2012.
  4. Office for National Statistics. Statistical Bulletin: Cancer survival in England: Patients diagnosed 2007-2011 and followed up to 2012. Newport: ONS; 2013.
  5. The National Cancer Registration Service, Eastern Office. Personal communication.
  6. Sant M, Allemani C, Santaquilani M, et al. EUROCARE-4. Survival of cancer patients diagnosed in 1995-1999. Results and commentary. Eur J Cancer 2009;45:931-91.
  7. Ries LAG, Eisner MP, Kosary CL, et al. SEER Cancer Statistics Review, 1975-2003. 5-year survival rates. Maryland, US: National Cancer Institute; 2005.
  8. Hicks ML, Phillips JL, Parham G, et al. The National Cancer Data Base report on endometrial carcinoma in African-American women. Cancer 1998;83(12):2629-37.
  9. Coleman MP, Rachet B, Woods LM, et al. Trends in socioeconomic inequalities in cancer survival in England and Wales up to 2001. BJC 2004;90(7):1367-73.
  10. Coleman MP, Babb P, Damiecki P, et al. Cancer Survival Trends in England and Wales, 1971-1995: Deprivation and NHS Region. Series SMPS No 61. London: ONS; 1999.
Updated: 10 December 2014