Uterine cancer incidence statistics

Cases

New cases of uterine cancer, 2016-2018, UK

 

Proportion of all cases

Percentage uterine cancer is of total cancer cases, 2016-2018, UK

 

Age

Peak rate of uterine cancer cases, 2016-2018, UK

Trend over time

Change in uterine cancer incidence rates since the early 1990s, Females, UK

 

Uterine cancer is the 4th most common cancer in females in the UK, accounting for 5% of all new cancer cases in females (2016-2018).In females and males combined, uterine cancer is the 13th most common cancer in the UK, accounting for 3% of all new cancer cases (2016-2018).[1-4]

Uterine cancer incidence rates (European age-standardised (AS) rate Open a glossary item) for females are significantly higher than the UK average in Wales and similar to the UK average in all other UK constituent countries.

For uterine cancer, like most cancer types, differences between countries largely reflect risk factor prevalence in years past.

Uterine Cancer (C54-C55), Average Number of New Cases Per Year, Crude and European Age-Standardised (AS) Incidence Rates per 100,000 Population, UK, 2016-2018

  England Scotland Wales Northern Ireland UK
Female Cases 8,051 846 544 263 9,703
Crude Rate 28.6 30.4 34.3 27.6 29.0
AS Rate 29.5 29.6 32.2 30.2 29.7
AS Rate - 95% LCL 29.2 28.4 30.7 28.1 29.4
AS Rate - 95% UCL 29.9 30.8 33.8 32.3 30.0
Persons Cases 8,051 846 544 263 9,703
Crude Rate 14.5 15.6 17.4 14.0 14.7
AS Rate 15.5 15.9 16.9 15.9 15.6
AS Rate - 95% LCL 15.3 15.2 16.1 14.8 15.5
AS Rate - 95% UCL 15.7 16.5 17.8 17.1 15.8

95% LCL and 95% UCL are the 95% lower and upper confidence limits around the AS Rate. Open a glossary item
 

References

  1. Data were provided by the National Cancer Registration and Analysis Service (part of Public Health England), on request through the Office for Data Release, July 2021. Similar data can be found here: https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/cancerregistrationstatisticsengland/previousReleases
  2. Data were provided by ISD Scotland on request, April 2020. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications.
  3. Data were published by the Welsh Cancer Intelligence and Surveillance Unit, Health Intelligence Division, Public Health Wales https://phw.nhs.wales/services-and-teams/welsh-cancer-intelligence-and-surveillance-unit-wcisu/cancer-incidence-in-wales-2002-2018/, March 2021.
  4. Data were provided by the Northern Ireland Cancer Registry on request, May 2020. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.

About this data

Data is for UK, 2016-2018, ICD-10 C54-C55.

Last reviewed:

Uterine cancer incidence is related to age, with the highest incidence rates being in older women. In the UK in 2016-2018, on average each year more than a quarter of new cases (27%) were in females aged 75 and over.[1-4]

Age-specific incidence rates rise steeply from around age 45-49 before dropping in the oldest age groups - a slightly different pattern from most cancers. The highest rates are in in the 75 to 79 age group.

Uterine cancer (C54-C55), Average Number of New Cases per Year and Age-Specific Incidence Rates per 100,000 Female Population, UK, 2016-2018

For uterine cancer, like most cancer types, incidence increases with age. This largely reflects cell DNA damage accumulating over time. Damage can result from biological processes or from exposure to risk factors. A drop or plateau in incidence in the oldest age groups often indicates reduced diagnostic activity perhaps due to general ill health.

The age distribution of uterine cancer cases probably reflects hormonal changes during and after the menopause.

References

  1. Data were provided by the National Cancer Registration and Analysis Service (part of Public Health England), on request through the Office for Data Release, July 2021. Similar data can be found here: https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/cancerregistrationstatisticsengland/previousReleases
  2. Data were provided by ISD Scotland on request, April 2020. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications.
  3. Data were published by the Welsh Cancer Intelligence and Surveillance Unit, Health Intelligence Division, Public Health Wales https://phw.nhs.wales/services-and-teams/welsh-cancer-intelligence-and-surveillance-unit-wcisu/cancer-incidence-in-wales-2002-2018/, March 2021.
  4. Data were provided by the Northern Ireland Cancer Registry on request, May 2020. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.

About this data

Data is for UK, 2016-2018, ICD-10 C54-C55.

Last reviewed:

Uterine cancer European age-standardised (AS) Open a glossary item incidence rates for females increased by 59% in the UK between 1993-1995 and 2016-2018.[1-4]

Over the last decade in the UK (between 2006-2008 and 2016-2018), uterine cancer AS incidence rates for females increased by 12%.

Uterine Cancer (C54-C55), European Age-Standardised Incidence Rates, Females, UK, 1993 to 2018

Uterine cancer incidence rates have increased overall in most broad age groups in females in the UK since the early 1990s, but have remained stable in some.[1-4] Rates in 0-24s have remained stable, in 25-49s have increased by 44%, in 50-59s have increased by 33%, in 60-69s have increased by 61%, in 70-79s have increased by 91% and in 80+s have increased by 49%.

Uterine Cancer (C54-C55), European Age-Standardised Incidence Rates per 100,000 Female Population, By Age, UK, 1993-2018

For uterine cancer, like most cancer types, incidence trends largely reflect changing prevalence of risk factors and improvements in diagnosis and data recording. Recent incidence trends are influenced by risk factor prevalence in years past, and trends by age group reflect risk factor exposure in birth cohorts.

References

  1. Data were provided by the National Cancer Registration and Analysis Service (part of Public Health England), on request through the Office for Data Release, July 2021. Similar data can be found here: https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/cancerregistrationstatisticsengland/previousReleases
  2. Data were provided by ISD Scotland on request, April 2020. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications.
  3. Data were published by the Welsh Cancer Intelligence and Surveillance Unit, Health Intelligence Division, Public Health Wales https://phw.nhs.wales/services-and-teams/welsh-cancer-intelligence-and-surveillance-unit-wcisu/cancer-incidence-in-wales-2002-2018/, March 2021.
  4. Data were provided by the Northern Ireland Cancer Registry on request, May 2020. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.

About this data

Data is for UK, 1993-2018, ICD-10 C54-C55.

Last reviewed:

The most common specific location for uterine cancers in the UK is the endometrium (2016-2018).[1-4] Variation of incidence by anatomical site may reflect the physical size of each site, and differences in risk factor exposure by site, among other factors.

Download this data

Cases and percentages may not sum due to rounding

References

  1. Data were provided by the Office for National Statistics on request, July 2014. Similar data can be found here: http://www.ons.gov.uk/ons/rel/vsob1/cancer-statistics-registrations--england--series-mb1-/index.html.
  2. Data were provided by ISD Scotland on request, April 2014. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications/index.asp.
  3. Data were provided by the Welsh Cancer Intelligence and Surveillance Unit on request, April 2014. Similar data can be found here: http://www.wales.nhs.uk/sites3/page.cfm?orgid=242&pid=59080.
  4. Data were provided by the Northern Ireland Cancer Registry on request, June 2014. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/CancerInformation/.

About this data

Data is for UK, 2016-2018, ICD-10 C54-C55. For some cases the specific location of the cancer is not recorded, this may be due to clinical or data recording factors.

Last reviewed:

The number of new uterine cancer cases in females on average each year in the UK is projected to rise from around 10,600 cases in 2023-2025 to around 11,800 cases in 2038-2040.[1]

Uterine cancer incidence rates are projected to fall by 2% in the UK between 2023-2025 and 2038-2040, to 29 cases per 100,000 females on average each year by 2038-2040.[1]

Uterine cancer (C54-C55), Observed and Projected Age-Standardised Incidence Rates, UK, 1993-2040

Download the data table (xlsx)

References

Calculated by the Cancer Intelligence Team at Cancer Research UK, February 2023. Age-period-cohort modelling approach described here, using 2020-based population projections (Office for National Statistics) and observed cancer incidence (1975-2018 for England, Scotland and Wales, 1993-2018 for Northern Ireland).

About this data

Projections are based on incidence data from 1975-2018 (England, Scotland and Wales) and 1993-2018 (Northern Ireland); the above figure presents all UK data from 1993-2018 (observed) and 2019-2040 (projected). Number of new cases and age-standardised rates are presented as annual averages for each 3-year rolling period. ICD-10 codes C54-C55.

Projections are based on observed incidence rates and therefore implicitly include changes in cancer risk factors and diagnosis. Confidence intervals are not calculated for the projected figures. Projections are by their nature uncertain because unexpected events in future could change the trend. It is not sensible to calculate a boundary of uncertainty around these already uncertain point estimates. Changes are described as 'increase' or 'decrease' if there is any difference between the point estimates.

More on projections methodology

Last reviewed:

Uterine cancer incidence rates (European age-standardised (AS) rates Open a glossary item) in England in females are 17% higher in the most deprived quintile compared with the least, and in males are  in the most deprived quintile compared with the least (2013-2017).[1]

It is estimated that there are around 640 more cases of uterine cancer each year in England than there would be if every deprivation quintile had the same age-specific crude incidence rates as the least deprived quintile. 

Uterine Cancer (C54-C55), Estimated Average Number of Excess Cases per Year and European Age-Standardised Incidence Rates per 100,000 Population, by Deprivation Quintile, England, 2013-2017

References

  1. 1.    Calculated by the Cancer Intelligence Team at Cancer Research UK, April 2020. Based on method reported in National Cancer Intelligence Network Cancer by Deprivation in England Incidence, 1996-2010 Mortality, 1997-2011. Using cancer incidence data 2013-2017 (Public Health England) and population data 2013-2017 (Office for National Statistics) by Indices of Multiple Deprivation 2015 income domain quintile, cancer type, sex, and five-year age band.

About this data

Data is for England, 2013-2017, ICD-10 C54-C55.

Last reviewed:

An estimated 70,200 women who had been diagnosed with uterine cancer between 1991 and 2010 were alive in the UK at the end of 2010.[1]

References

  1. Macmillan Cancer Support and National Cancer Registration and Analysis Service. Cancer Prevalence UK Data Tables. London: NCRAS; 2015.

About this data

Data is for: Great Britain (1991-2010) and Northern Ireland (1993-2010), ICD-10 C45-C55

Last reviewed:

Cancer stats explained

See information and explanations on terminology used for statistics and reporting of cancer, and the methods used to calculate some of our statistics.

Citation

You are welcome to reuse this Cancer Research UK content for your own work.
Credit us as authors by referencing Cancer Research UK as the primary source. Suggested styles are:

Web content: Cancer Research UK, full URL of the page, Accessed [month] [year].
Publications: Cancer Research UK ([year of publication]), Name of publication, Cancer Research UK.
Graphics (when reused unaltered): Credit: Cancer Research UK.
Graphics (when recreated with differences): Based on a graphic created by Cancer Research UK.

When Cancer Research UK material is used for commercial reasons, we encourage a donation to our life-saving research.
Send a cheque payable to Cancer Research UK to: Cancer Research UK, 2 Redman Place, London, E20 1JQ or

Donate online

Acknowledgements

We are grateful to the many organisations across the UK which collect, analyse, and share the data which we use, and to the patients and public who consent for their data to be used. Find out more about the sources which are essential for our statistics.