Last year in the UK over 60,000 cancer patients enrolled on clinical trials aimed at improving cancer treatments and making them available to all.
A study looking at a walking programme during chemoradiotherapy for rectal cancer (REx)
Please note - this trial is no longer recruiting patients. We hope to add results when they are available.
This study is to see if a walking programme is helpful for people with rectal cancer. It is for people who have recently been diagnosed with cancer of the
More about this trial
Exercise can improve
In this study, researchers are looking at a walking programme that people with rectal cancer can do from home while they are having chemoradiotherapy.
The aims of the study are to find out
Who can enter
You may be able to join this study if all of the following apply. You
- Have recently been diagnosed with rectal cancer
- Are due to have
chemoradiotherapybefore surgery to treat your cancer
- Are at least 18 years old
You cannot join this study if any of these apply.
- You have already had treatment for rectal cancer
- The walking programme is too easy for your level of physical
- You have had any other type of cancer in the past
- You have any other serious medical condition or mental health problem which means the study team don’t think you should take part
This is a pilot study. The researchers need 80 people to take part. It is randomised. The people taking part are put into 1 of 2 groups at random. Neither you nor your doctor will be able to decide which group you are in.
People in one group take part in the walking programme. This is called the intervention group. People in the other group do not take part in the programme. This is called the control group.
If you are in the control group, the researchers will ask you to continue with your usual physical activity.
If you are in the intervention group, your walking programme begins when you start chemoradiotherapy and finishes in the weeks before you have surgery to remove your cancer. The walking programme will last for about 4 months in total.
The study team plan a walking programme suitable for your level of fitness. They count the number of steps you walk each week with a small device called a pedometer. This is strapped onto your clothes.
The aim is to increase the number of steps you walk each week. You can ask a friend or relative to be your walking partner to help motivate you. The researchers will ask you to keep a diary to record of the number of steps you walk each day. And a research nurse will phone you every 2 weeks to see how you are getting on.
The researchers will ask everybody taking part to fill out 2 questionnaires before you have chemoradiotherapy, when you finish the walking programme and before you have surgery. The questionnaires will ask about side effects and how you’ve been feeling. This is called a quality of life study.
You see the study team and have some tests before you can take part in the study. These include
- A test to see how far you can walk in 6 minutes
- A test to check your muscle strength
They will repeat the tests before your surgery. They will ask everybody taking part to wear a small device called an accelerometer for 7 days
- Before chemoradiotherapy starts
- When the walking programme is finished
This is to measure your usual level of activity.
The researchers don’t think that the walking involved will cause you any problems.
How to join a clinical trial
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Miss Susan Moug
Chief Scientist Office (CSO)
NHS Greater Glasgow and Clyde