A study looking at developing new treatments for myeloma

Cancer type:






This study is looking at developing new treatments for myeloma in the laboratory Open a glossary item.

Myeloma is a type of cancer that develops from cells in the bone marrow Open a glossary item called plasma cells. In this study doctors want to use some of the myeloma cells from your blood and bone marrow to test the new treatment in the laboratory.

They also want blood and bone marrow from healthy volunteers who do not have myeloma.

The aims of this study are to

  • Find out if the new drugs in the laboratory kill myeloma cells
  • Develop a new test to help treat myeloma in the future

Who can enter

You may be able to enter this trial if you

  • Are having your myeloma treatment at Imperial College Healthcare NHS Trust, London
  • Have one of the following  types of myeloma - monoclonal gammopathy, smouldering myeloma, multiple myeloma or plasmacytoma
  • Do not have myeloma (are a healthy volunteer)
  • Are at least 18 years old

You cannot enter this trial if you

  • Have any other illness that would make you unsuitable for the study
  • Are pregnant or breastfeeding

Trial design

This study will recruit 100 people with myeloma and 50 people without.

Everybody taking part will have a blood test and bone marrow test once a year for 5 years.

Hospital visits

If you have myeloma there are no extra hospital visits as part of this trial. You give blood and bone marrow samples when you see the doctor as part of your routine care.

If you are a healthy volunteer the doctors will organise your visit at a time convenient for you.

Side effects

Side effects of bone marrow tests include discomfort and bruising at your biopsy site. You may need some mild painkillers to take home or the doctor may suggest you take paracetamol. Very rarely you may also have bleeding, infection and pain.

You may have a small bruise where you had your blood test.



Recruitment start:

Recruitment end:

How to join a clinical trial

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Chief Investigator

Professor Guido Franzoso

Supported by

Imperial College Healthcare NHS Trust
Medical Research Council (MRC)
NIHR Clinical Research Network: Cancer

Questions about cancer? Contact our information nurses

Freephone 0808 800 4040

Last review date

CRUK internal database number:


Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Charlie took part in a trial to try new treatments

A picture of Charlie

“I think it’s really important that people keep signing up to these type of trials to push research forward.”

Last reviewed:

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