A study to find out why some bowel screening test results show blood when there is no cancer

Please note - this trial is no longer recruiting patients. We hope to add results when they are available.

Cancer type:

Bowel (colorectal) cancer





This study is trying to find out why some people’s bowel screening test results show blood in the stool when they don’t have bowel cancer.

Everyone in England between the ages of 60 and 69 receives an invitation to take part in the NHS Bowel Cancer Screening Programme. Along with a letter they receive a kit to collect a tiny amount of stool (faeces).

The stool is tested for blood. If the results show that there is blood in the sample, you have a further bowel test called a colonoscopy Open a glossary item to check for cancer. But most people who have a colonoscopy don’t have bowel cancer.

The researchers want to understand more about why this is so.

Who can enter

You may be able to enter this study if you are attending a screening clinic at your local hospital before having a colonoscopy.

Trial design

This is an observational study. It will recruit 2,500 people. A copy of your information is stored on a secure computer database at Oxford. The researchers will look at this information along with the results of your colonoscopy.

They may send you a follow up questionnaire a year later. It will ask you about any illnesses you have had since your screening. They will give you a pre paid addressed envelope to return the questionnaire in.

Hospital visits

There are no extra hospital visits if you agree to take part in this study.

Side effects

There are no side effects to taking part in this study.

Recruitment start:

Recruitment end:

How to join a clinical trial

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Chief Investigator

Prof Julietta Patnick

Supported by

Cancer Research UK
NHS Bowel Cancer Screening Programme
National Institute for Health Research Cancer Research Network (NCRN)
University of Oxford

Questions about cancer? Contact our information nurses

Freephone 0808 800 4040

Last review date

CRUK internal database number:

Oracle 8743

Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Alan took part in a clinical trial for bowel cancer patients

A picture of ALan

“I think it’s essential that people keep signing up to these type of trials to push research forward.”

Last reviewed:

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