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Treatment for stomach cancer

Treatment options for stomach cancer

The treatment for stomach cancer depends on a number of factors. Your doctor will discuss your treatment, its benefits and the possible side effects with you.

Deciding what treatment you need

A team of doctors and other professionals discuss the best treatment and care for you. They are called a multidisciplinary team (MDT).

Most people are referred to a specialist MDT. You might go to a different hospital if there isn't a specialist MDT at your local hospital.

The team usually includes:

  • a specialist surgeon

  • cancer specialists (oncologists) who treat cancer with cancer drugs (medical oncologist) and radiotherapy (clinical oncologist)

  • a specialist cancer nurse (also called a clinical nurse specialist)

  • a pathologist who examines any cancer or tissue the surgeon removes

  • a radiologist who looks at your scans and x-rays

  • an endoscopist who looks inside your food pipe and stomach using a flexible tube

  • a dietitian who offers support and advice about eating and drinking

  • a palliative care doctor who specialises in controlling cancer symptoms

Your treatment depends on:

  • where the cancer is in your stomach

  • how far it has grown or spread (the stage)

  • the type of cancer

  • how abnormal the cells look under a microscope (the grade)

  • whether the cancer has spread to another part of the body (this spread is also called secondary cancer)

  • your general health and level of fitness

The MDT will discuss your treatment, its benefits and possible side effects with you.  This is a good time to ask any questions you might have. You then sign a consent form.

Treatment overview

The main treatments are:

  • surgery    

  • chemotherapy

  • targeted or immunotherapy cancer drugs 

  • radiotherapy 

You might have one or more of these treatments depending on the stage of your cancer. You may have other treatments, such as a stent, to control symptoms.

Surgery

You might have surgery if your stomach cancer hasn't spread. Doctors remove:

  • cancer from the lining of the stomach using an endoscope (endoscopic mucosal resection or endoscopic submucosal dissection)

  • all or part of your stomach (a partial or total gastrectomy)

You may have surgery with other treatments, such as chemotherapy. And some people have surgery to relieve the symptoms of advanced cancer. 

Read about surgery for stomach cancer

Chemotherapy

Chemotherapy uses anti cancer (cytotoxic) drugs to destroy cancer cells. The drugs circulate throughout the body in your bloodstream.

You might have chemotherapy before and after surgery. Or you might have chemotherapy as your main treatment if your cancer has spread and you can't have surgery. 

Chemotherapy for advanced cancer can relieve symptoms. It can also control the cancer and improve your quality of life for a time.

Read about chemotherapy for stomach cancer

Radiotherapy

Radiotherapy uses high energy rays to destroy cancer cells.

You might have radiotherapy combined with chemotherapy (chemoradiotherapy). Or you might have radiotherapy to control the symptoms of advanced cancer. 

Read about radiotherapy for stomach cancer

Targeted and immunotherapy cancer drugs

Targeted cancer drugs work by targeting the differences in cancer cells that help them to grow and survive. Other drugs help the immune system to attack cancer. These are called immunotherapy. 

You might have targeted or immunotherapy cancer drugs as part of your treatment for advanced stomach cancer.

Read about targeted cancer drugs and immunotherapy

Other treatments to relieve symptoms

The cancer might block the entrance to your stomach or bowel. This can cause pain, sickness and make you feel very unwell. 

Your doctor might recommend:

  • a tube called a stent that goes into your stomach to allow food to pass through

  • laser therapy which uses hot beams of light to burn away cancer cells causing the blockage

Read more about other treatments and controlling symptoms of advanced stomach cancer

Treatment by stage

High grade dysplasia

The main treatment is via an endoscope to remove the abnormal cells from the lining of the stomach. You might have an endoscopic mucosal resection (EMR) or endoscopic submucosal dissection (ESD). 

Stage 1

Surgery is the main treatment. 

You might have surgery to remove all or part of the stomach. If your cancer is stage 1B, you might have chemotherapy before and after surgery.

For very small, early stage cancers you may have endoscopic surgery. You don't usually need any other treatment.

Stage 2 and 3 

You usually have surgery to remove all or a part of your stomach. And have chemotherapy before and after surgery. 

If you haven't had chemotherapy before surgery, you might have:

  • chemotherapy combined with radiotherapy (chemoradiotherapy) after surgery

  • chemotherapy on its own after surgery 

Your doctor will discuss your options with you.

Stage 4

Treatment aims to control the cancer and maintain a good quality of life. You might have:

  • chemotherapy

  • radiotherapy

  • symptom control, for example treatment to help you swallow food

  • targeted or immunotherapy cancer drugs

Find out more about the stages of stomach cancer

Clinical trials to improve treatment

Your doctor may ask if you’d like to take part in a clinical trial.

Doctors and researchers do trials to:

  • improve treatment

  • reduce the side effects of treatment

  • develop new treatments

Research and clinical trials

Getting a second opinion

Some people like to get an opinion from a second doctor. This is before they decide on their treatment. Most doctors are happy to refer you to another NHS specialist if you would find this helpful. 

Go to more information about getting a second opinion

Last reviewed: 13 Mar 2025

Next review due: 13 Mar 2028

Stages of stomach cancer

The stage of a cancer tells you how big it is and how far it’s spread. It helps your doctor decide which treatment you need.

Types and grades of stomach cancer

The type of stomach cancer you have depends on what type of cell it started in. The grade tells you how abnormal the cells look under a microscope. Adenocarcinoma is the most common type of stomach cancer.

Treatment for stomach cancer

Your treatment depends on whereabouts your cancer is in the stomach. How big it is, whether it has spread anywhere else in your body and your general health.

Living with stomach cancer

There is support available to help you cope during and after stomach cancer treatment. This includes diet tips to help you eat well.

Research into stomach cancer

Researchers are looking at the causes, diagnosis and treatment of stomach cancer.

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