PET-CT scan

A PET-CT scan combines a CT scan and a PET scan into one to give detailed information about your lymphoma.

A PET-CT scan gives more information than a CT scan. It shows the stage of the Hodgkin lymphoma and how far it has spread.

The CT scan takes a series of x-rays from all around your body. The PET scan uses a mildly radioactive drug to show up areas of your body where cells are more active than normal. 

You usually have a PET-CT scan in the x-ray (radiology) department as an outpatient. These scanners tend to be only in the major cancer hospitals. So you might have to travel to another hospital to have one. A radiographer operates the scanner. It usually takes between 30 and 60 minutes.

Why you might have a PET-CT scan

You might have a PET-CT scan to see if the Hodgkin lymphoma has spread to other areas of your body, including the bone marrow.

Doctors may also use PET-CT scans during and after treatment. If it looks as though there are still swollen (enlarged) lymph nodes after treatment, a PET-CT scan can help show if this is due to scar tissue or there are still active lymphoma cells.

Preparing for your PET-CT scan

For most PET-CT scans, you need to stop eating about 4 to 6 hours beforehand. You can usually drink water during this time. You might have instructions not to do any strenuous exercise for 24 hours before the scan.

Call the number on your appointment letter if not eating is a problem for you, for example if you have diabetes. You might need to adapt your diet and sugar control and your appointment time could change.

Some people feel claustrophobic when they're having a scan. Contact the department staff before your test if you’re likely to feel like this. They can take extra care to make sure you’re comfortable and that you understand what’s going on.

Your doctor can arrange to give you medicine to help you relax, if needed.

What happens?

Your radiographer will ask you to change into a hospital gown. You have to remove any jewellery and other metal objects such as a belt, wired bra, hair clips and coins. Metal interferes with the images produced by the scanner. Wearing trousers or a skirt with an elasticated waistband and no zips might be useful, as you might not need to remove them.

You have the injection of the radioactive tracer about an hour before the scan. You have this injection through a small plastic tube in your arm (a cannula). It's only a small amount of radiation.

You need to rest and avoid moving too much during this hour. This allows the radioactive tracer to spread through your body and into your tissues.

In the scanning room

Your radiographer takes you into the scanning room. The PET-CT machine is large and shaped like a doughnut.

You have most scans lying down on the machine couch on your back.

Once you’re in the right position, your radiographer leaves the room. They can see you on a TV screen or through a window from the control room. You can talk to each other through an intercom.

Having the PET-CT scan

The couch slowly slides backwards and forwards through the scanner. The machine takes pictures as you move through it. 

The scan is painless but can be uncomfortable because you have to stay still. Tell your radiographer if you’re getting stiff and need to move.

It’s not particularly noisy and in most places the radiographers will be able to play music for you.

When it’s over, your radiographer will come back into the room and lower the couch so you can get up.

This 3-minute video shows you what happens when you have a PET-CT or PET scan.

After your PET-CT scan

Your radiographer removes the cannula from your arm before you go home.

You can then eat and drink normally.

The radiation in the radioactive tracer is very small. Drinking plenty of fluids after your scan helps to flush the radiotracer out of your system.

The radioactive tracer gives off very small levels of radiation that go away very quickly. As a precaution, you should avoid close contact with pregnant women, babies and young children for 6 hours after the scan. 

You need someone to take you home and stay overnight if you’ve had medicine to help you relax (sedative). You also shouldn’t drive, drink alcohol, operate heavy machinery or sign any legally binding documents for 24hours.

If you are travelling abroad within a week of your scan, it may be a good idea to take your appointment letter with you to show that you have had a scan. Most airports have sensitive radiation monitors which may pick up the trace of radiation following your test.

Getting your results

You should get your results within 1 or 2 weeks. You normally get them at your next clinic appointment.

Waiting for test results can be worrying. You might have contact details for a specialist cancer nurse. You can get in touch with them for information and support if you need to. It may help to talk to a close friend or relative about how you feel.

You can also call the Cancer Research UK nurses on freephone 0808 800 4040. The lines are open from 9am to 5pm, Monday to Friday.

Possible risks

A PET-CT scan is a safe test for most people. But like all medical tests it has some risks. Your doctor and radiographer make sure the benefits of having the test outweigh these risks. 

Some of the possible risks include:

Pregnancy

Pregnant women should only have the scan in an emergency. There’s a risk that the radiation could harm the developing baby. Contact the department beforehand if you are or think you might be pregnant.

Breastfeeding

If you are breastfeeding, let the department know a few days before your appointment. They will let you know if you need to stop breastfeeding for a length of time after having the radioactive tracer. You might need to store enough expressed milk for at least one feed.

Radiation

Exposure to radiation during a PET-CT scan can slightly increase your risk of developing cancer in the future. Talk to your doctor if this worries you. 

Bruising and swelling

You might get a small bruise around the area where they put the needle in. 

There is a risk that the radioactive tracer will leak outside the vein. This can cause swelling and pain in your arm but it's rare. 

Allergic reaction

Rarely, people have an allergic reaction to the radioactive tracer. This most often starts with weakness, sweating and difficulty breathing. Tell your radiographer immediately if you feel unwell.

  • Evidence-based indications for the use of PET-CT in the UK
    The Royal College of Radiologists, 2016 

  • Hodgkin’s Lymphoma: ESMO clinical practice guidelines for diagnosis, treatment and follow-up
    DA Eichenauer, A Engert, M André and others
    Annals of Oncology, 2018, Volume 29 (Supplement 4)

  • Guidelines for the first line management of classical Hodgkin lymphoma
    GA Follows, KM Ardeshna, SF Barrington and others
    British Journal of Haematology, 2014, Volume 166

Last reviewed: 
25 Sep 2020
Next review due: 
25 Sep 2023

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