Vulval cancer incidence statistics

Cases

New cases of vulval cancer, 2014, UK

 

Proportion of all cases

Percentage vulval cancer is of total cancer cases, 2014, UK

 

Age

Peak rate of vulval cancer cases, 2012-2014, UK

 

Trend over time

Change in vulval cancer incidence rates since the early 1990s, UK

Vulval cancer is the 20th most common cancer among females in the UK, accounting for less than 1% of all new cases of cancer in female cases (2014).[1-4]

In 2014, there were 1,289 new cases of vulval cancer in the UK.[1-4] The crude incidence rate Open a glossary item shows that there are 4 new vulval cancer cases for every 100,000 females in the UK.

The European age-standardised incidence rate Open a glossary item (AS rate) do not differ significantly between the constituent countries of the UK.[1-4]

Vulval Cancer (C51), Number of New Cases, Crude and European Age-Standardised (AS) Incidence Rates per 100,000 Population, Females, UK, 2014

England Wales Scotland Northern Ireland UK
Cases 1,054 71 130 34 1,289
Crude Rate 3.8 4.5 4.7 3.6 3.9
AS Rate 3.9 4.1 4.6 4.1 4.0
AS Rate - 95% LCL 3.6 3.2 3.8 2.7 3.7
AS Rate - 95% UCL 4.1 5.1 5.4 5.4 4.2

95% LCL and 95% UCL are the 95% lower and upper confidence limits Open a glossary item around the AS Rate Open a glossary item

For vulval cancer, like most cancer types, differences between countries largely reflect risk factor prevalence in years past.

References

  1. Data were provided by the Office for National Statistics on request, June 2016. Similar data can be found here: http://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/cancerregistrationstatisticsengland/previousReleases.
  2. Data were provided by ISD Scotland on request, May 2016. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications/.
  3. Data were provided by the Welsh Cancer Intelligence and Surveillance Unit, Health Intelligence Division, Public Health Wales on request, June 2016. Similar data can be found here: http://www.wcisu.wales.nhs.uk.
  4. Data were provided by the Northern Ireland Cancer Registry on request, May 2016. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.

About this data

Data is for: UK, 2014, ICD-10 C51

Last reviewed:

Vulval cancer incidence is strongly related to age, with the highest incidence rates being in older females. In the UK in 2012-2014, on average each year almost half (55%) cases were diagnosed in females aged 70 and over.[1-4]

Age-specific incidence rates rise gradually from around age 35-39, and more sharply from around age 65-69, reaching the highest rates in the 90+ age group.[1-4]

Vulval Cancer (C51), Average Number of New Cases per Year and Age-Specific Incidence Rates, Females, UK, 2012-2014

For vulval cancer, like most cancer types, incidence increases with age. This largely reflects cell DNA damage accumulating over time. Damage can result from biological processes or from exposure to risk factors. A drop or plateau in incidence in the oldest age groups often indicates reduced diagnostic activity perhaps due to general ill health.

References

  1. Data were provided by the Office for National Statistics on request, June 2016. Similar data can be found here: http://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/cancerregistrationstatisticsengland/previousReleases.
  2. Data were provided by ISD Scotland on request, May 2016. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications/.
  3. Data were provided by the Welsh Cancer Intelligence and Surveillance Unit, Health Intelligence Division, Public Health Wales on request, June 2016. Similar data can be found here: http://www.wcisu.wales.nhs.uk.
  4. Data were provided by the Northern Ireland Cancer Registry on request, May 2016. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/

About this data

Data is for UK, 2012-2014, ICD-10 C51

Last reviewed:

Vulval cancer incidence rates have increased by 16% in females in the UK since the early 1990s.[1-3] This includes a period of stability followed by an increase. Vulval cancer incidence rates remained stable in Great Britain between 1979-1981 and 1991-1993.[1-3]

European age-standardised Open a glossary item (AS) rates remained stable between 1993-1995 and 2005-2007, then increased by 11% between 2005-2007 and 2012-2014.

Over the last decade in the UK (between 2003-2005 and 2012-2014), vulval cancer AS incidence rates in females have increased by 11%.[1-4]

Vulval Cancer (C51), European Age-Standardised Incidence Rates, Females, UK, 1993-2014

Vulval cancer incidence rates have increased overall for the younger adult age groups in the UK since the early 1990s, whilst remaining stable for older age groups.[1-4]

Rates have increased in females aged 25-49, 50-59 and 60-69. The largest increases have been in 50-59 year olds, for whom European AS incidence rates increased by 92% between 1993-1995 and 2012-2014. Rates have remained stable in females aged 70-79 and 80+.

Vulval Cancer (C51), European Age-Standardised Incidence Rates, by Age, UK, Females, 1993-2014​

For vulval cancer, like most cancer types, incidence trends largely reflect changing prevalence of risk factors and improvements in diagnosis and data recording. Recent incidence trends are influenced by risk factor prevalence in years past, and trends by age group reflect risk factor exposure in birth cohorts.

References

  1. Data were provided by the Office for National Statistics on request, June 2016. Similar data can be found here: http://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/cancerregistrationstatisticsengland/previousReleases
  2. Data were provided by ISD Scotland on request, May 2016. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications/
  3. Data were provided by the Welsh Cancer Intelligence and Surveillance Unit, Health Intelligence Division, Public Health Wales on request, June 2016. Similar data can be found here: http://www.wcisu.wales.nhs.uk
  4. Data were provided by the Northern Ireland Cancer Registry on request, May 2016. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/

About this data

Data is for UK, 1993-2014, ICD-10 C51

Last reviewed:

Squamous cell carcinomas (SCC) account for more than 90% of vulval cancers.[1] The other 10% includes melanomas, sarcomas, basal cell carcinomas Open a glossary item and adenocarcinomas Open a glossary item.[2]

References

  1. Woolas RP, Shepherd JH. Current developments in the management of vulval carcinoma. In O'Brian PMS (Eds). The Yearbook of Obstetrics and Gynecology. London, RCOG Press: 1999.
  2. Daling JR, Sherman JH. Cancers of the vulva and vagina. In Schottenfeld D, Fraumeni J (Eds). Cancer epidemiology and prevention. London:OUP; 1996.
Last reviewed:

The lifetime risk of developing vulval cancer is around 1 in 275 for women, in 2012 in the UK.[1]

The lifetime risk for vulval cancer has been calculated to account for the possibility that someone can have more than one diagnosis of vulval cancer over the course of their lifetime (‘Adjusted for Multiple Primaries’ (AMP) method).[2]

References

  1. Lifetime risk estimates calculated by the Statistical Information Team at Cancer Research UK. Based on data provided by the Office of National Statistics, ISD Scotland, the Welsh Cancer Intelligence and Surveillance Unit and the Northern Ireland Cancer Registry, on request, December 2013 to July 2014.
  2. Sasieni PD, Shelton J, Ormiston-Smith N, et al. What is the lifetime risk of developing cancer?: The effect of adjusting for multiple primaries. Br J Cancer, 2011. 105(3): p. 460-5.
Last reviewed:

 There is evidence for an association between vulval cancer incidence and deprivation in England.[1] England-wide data for 2006-2010 show European age-standardised Open a glossary item incidence rates are 82% higher for females living in the most deprived areas compared with the least deprived.[1]

Vulval Cancer (C51), European Age-Standardised Incidence Rates by Deprivation Quintile, Females, England, 2006-2010

The estimated deprivation gradient in vulval cancer incidence between females living in the most and least deprived areas in England has widened in the period 1996-2010.[1] It has been estimated that there would have been around 240 fewer cancer cases each year in England during 2006-2010 if all females experienced the same incidence rates as the least deprived.[1

Last reviewed:

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