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Having surgery for stomach cancer

Endoscopic surgery for stomach cancer

You might have endoscopic surgery to remove abnormal areas in the lining of the stomach.

When you might have endoscopic surgery

You might have endoscopic surgery to remove:

  • high grade dysplasia in the stomach

  • very early stage cancers that are small and within the inner layers of the stomach

Go to information about the staging of stomach cancer

Types of endoscopic surgery

Your doctor uses a long flexible tube (endoscope) with a tiny camera and light on the end to look inside your stomach. They remove the abnormal area by passing special instruments through the tube.

Your doctor will use one of the following to do this:

  • endoscopic submucosal dissection (ESD)

  • endoscopic mucosal resection (EMR)

These operations are very similar. Your doctor will tell you which one you are going to have.

Preparing for your surgery

You will have a blood test 2 days beforehand to check how well your blood clots.

Tell your doctor if you're having medicine that changes how your blood clots. This includes:

  • aspirin

  • clopidogrel

  • arthritis medicines

  • warfarin or heparin

  • apixaban or rivaroxaban

Your doctor will tell you if you need to stop taking any other medicines.

You can't eat for 6 to 8 hours before the surgery, but you might be able to drink sips of water up to 2 hours before your appointment. Your doctor or nurse gives you written instructions about this beforehand.

Talk to your doctor if not eating could be a problem for you. For example, if you have diabetes.

What happens?

You have the surgery in the endoscopy unit in hospital. It is done by a specialist endoscopist. You will have had a gastroscopy as one of the tests to diagnose the cancer. The preparation for EMR and ESD is the same as for a gastroscopy.

Your doctor will explain what they are going to do and you sign a consent form. This is a good time to ask any questions you might have.

Diagram of an endoscopy.

Before the operation

When you arrive, the nurse will ask you to go into a cubicle to change into a hospital gown.

You lie down on the couch and an anaesthetist puts a small tube (cannula) into a vein in your arm or hand. They then attach a drip that contains a ​​. This will make you very sleepy. It takes a few minutes for this to work. You will have oxygen through a small plastic tube or sponge which sits just inside your nostril. A plastic clip on your finger will measure your heart rate and oxygen levels, and your nurse will check your blood pressure.

The doctor will also spray local anaesthetic in the back of your throat to make it easier to swallow the endoscope.

Some people need to have the operation under a general anaesthetic. So you will be unconscious. Your doctor will tell you if this applies to you.

During the operation

Once you’re sleepy, your doctor passes the endoscope down your throat. Using the endoscope they inject fluid into the layer of cells below the cancer or abnormal area. The fluid lifts the abnormal area away from the deeper layers of the stomach wall.

Endoscopic mucosal resection (EMR)

Your doctor removes the abnormal area of tissue using a thin wire (snare). The tissue is sometimes removed in pieces.

Endoscopic submucosal dissection (ESD)

Your doctor uses a small knife to remove the abnormal area of tissue, as well as a small amount of the normal tissue around it. The tissue is usually removed in one piece.  

They collect the tissue and send it to the laboratory to look at under a microscope.

Both operations take between 30 minutes and 2 hours depending on how much of the lining they need to remove.

After the operation

You need to rest for a while afterwards. You probably won’t remember having the operation.

Whether you can go home the same day or stay in hospital overnight will vary. If you go home on the same day, you need someone to take you home and stay with you for 24 hours.

You usually only drink liquids for the first day or so. Then you can move onto a soft diet and gradually build up to a normal diet again. Your nurse will give you specific information about what you can eat and drink.

You could have:

  • mild chest pain like heartburn

  • mild discomfort when you eat food

  • bloating and discomfort lasting a few hours

You can take paracetamol to control any pain you might have. Don’t take aspirin or non-steroidal painkillers such as ibuprofen.

Possible risks

Your doctors will make sure the benefits of having the surgery outweigh the possible risks. These include:

  • bleeding – contact the hospital if you start vomiting blood or if your poo is black

  • a sore throat that can last for up to 24 hours – contact the hospital if you have severe pain in your throat, chest or tummy (abdomen)

  • fluid going into your lungs from your mouth – this rarely happens as a nurse removes the fluid from your mouth during the operation

  • a reaction to the sedative making you breathless

  • a small tear (perforation) in the food pipe, stomach or small bowel - this is rare but can be serious

Follow up

At your first follow up appointment, your doctor:

  • gives you the results of the surgery

  • examines you

  • asks how you are and if you've had any problems  

This is also your opportunity to ask any questions. Write down any questions you have before your appointment to help you remember what to ask. Taking someone with you can also help you to remember what the doctor says.

How often you have follow up appointments depends on the results of your surgery. Ask your doctor how often you need to have these and what they will involve.

You usually have an endoscopy 3 months later to check that your stomach is healing.

Last reviewed: 13 Mar 2025

Next review due: 13 Mar 2028

Stages of stomach cancer

The stage of a cancer tells you how big it is and how far it’s spread. It helps your doctor decide which treatment you need.

Types and grades of stomach cancer

The type of stomach cancer you have depends on what type of cell it started in. The grade tells you how abnormal the cells look under a microscope. Adenocarcinoma is the most common type of stomach cancer.

Coping with stomach cancer

Coping with cancer can be difficult. Help and support is available. There are things you can do, people to help and ways to cope with a diagnosis of stomach cancer.

Survival for stomach cancer

Survival depends on many factors including the stage of your stomach cancer when you are diagnosed and how it has responded to treatment. The figures for stomach cancer survival can only be used as a general guide.

Treatment for stomach cancer

Your treatment depends on whereabouts your cancer is in the stomach. How big it is, whether it has spread anywhere else in your body and your general health.

Gastroscopy

A gastroscopy is a test that looks at the inside of your food pipe (oesophagus), stomach and the first part of your small intestine (small bowel).

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