Treatment
Your treatment depends on how far your disease has grown or spread (the stage), your risk score and your symptoms. A team of doctors and other professionals discuss the best treatment and care for you.
Find out more about staging and risk scores
Usually a team of doctors and other health professionals work together. They consider your case and decide together on the best treatment for you. They specialise in different aspects of treatment, but work together as a multi disciplinary team (MDT).
The team may include:
cancer specialists who treat cancer with cancer drugs (medical oncologist)
a GTD specialist nurse (clinical nurse specialist)
a pathologist who examines any cancer or molar tissue
physiotherapists
a radiologist who looks at your scans and x-rays
psychologists and counsellors
Most people with an invasive mole or choriocarcinoma will have chemotherapy treatment. A few women might need surgery.
Chemotherapy uses anti cancer drugs to destroy cancer cells. The drugs circulate throughout the body in the bloodstream.
Immunotherapy drugs help your immune system attack cancer. Although rare, some women’s disease might develop resistance to chemotherapy. So they have treatment with immunotherapy drugs.
The type of cancer drug treatment you need will depend on your stage and risk score.
Read more about cancer drug treatment
Your doctor might suggest surgery to remove the womb. This is called a hysterectomy. You might have this if your cancer doesn't respond to chemotherapy. Or if you have completed your family and do not want to have chemotherapy.
You might still need to have chemotherapy after a hysterectomy. Your specialist team will discuss this with you.
In very rare situations, women might have surgery to remove disease that has spread to other parts of the body.
To have treatment you go to one of the UK specialist centres:
Charing Cross Hospital, London
Weston Park Hospital, Sheffield
The amount of time you need to spend in hospital depends on the treatment you have. You are likely to need to stay in hospital for at least a week at the start of treatment.
The overall for chemotherapy can last up to 6 months. You may be able to have much of the treatment as an outpatient at your local hospital.
Following treatment, your healthcare team will monitor you closely. You have regular blood and urine tests to check your levels of hCG hormone. This is to:
check that the disease has completely gone and
look for any signs of it coming back
Last reviewed: 15 Sept 2025
Next review due: 15 Sept 2028
The main treatment for invasive mole and choriocarcinoma is chemotherapy. Some women might have immunotherapy drugs.
You will be closely monitored with blood and urine tests during and after your treatment. This is to check the levels of human gonadotrophic hormone (hCG).
The stage of an invasive mole or choriocarcinoma tells you how far it has spread. Your doctors will look at this and other risk factors to plan your treatment.
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