Anal cancer incidence statistics

Cases

New cases of anal cancer, 2013, UK

 

Proportion of all cases

Percentage anal cancer is of total cancer cases, 2013, UK

 

Age

Age that around half of anal cancer cases are diagnosed, 2011-2013, UK

 

Trend since 1970s

Anal cancer incidence rates have increased since the late 1970s, GB

 

Anal cancer accounts for 0.4% of all new cases in the UK (2013), accounting for 0.2% of all male cases, and 0.5% of all female cases.[1-4]

In 2013, there were 1,233 new cases of anal cancer in the UK: 436 (35%) in males and 797 (65%) in females, giving a male:female ratio of around 5:10.[1-4] The crude incidence rate Open a glossary item shows that there is 1 new anal cancer case for every 100,000 males in the UK, and 2 for every 100,000 females.

Anal cancer is one of the few cancers which can occur in both sexes but is more common in females than males. This is at least partly due to sex differences in exposure to risk factors.[5-7]

The European age-standardised incidence rate Open a glossary item (AS rate) does not differ significantly between the constituent countries of the UK for either sex.[1-4]

Anal Cancer (C21), Number of New Cases, Crude and European Age-Standardised (AS) Incidence Rates per 100,000 Population, UK, 2013

England Wales Scotland Northern Ireland UK
Male Cases 369 24 32 11 436
Crude Rate 1.4 1.6 1.2 1.2 1.4
AS Rate 1.6 1.8 1.3 1.5 1.6
AS Rate - 95% LCL 1.5 1.1 0.9 0.6 1.5
AS Rate - 95% UCL 1.8 2.5 1.8 2.4 1.8
Female Cases 646 58 79 14 797
Crude Rate 2.4 3.7 2.9 1.5 2.4
AS Rate 2.5 3.5 2.8 1.8 2.5
AS Rate - 95% LCL 2.3 2.6 2.2 0.8 2.4
AS Rate - 95% UCL 2.7 4.4 3.5 2.7 2.7
Persons Cases 1,015 82 111 25 1,233
Crude Rate 1.9 2.7 2.1 1.4 1.9
AS Rate 2.1 2.6 2.2 1.6 2.1
AS Rate - 95% LCL 1.9 2.1 1.8 1.0 2.0
AS Rate - 95% UCL 2.2 3.2 2.6 2.3 2.2

95% LCL and 95% UCL are the 95% lower and upper confidence limits Open a glossary item around the AS Rate Open a glossary item

ASR calculated with ESP2013. Not comparable with ASRs calculated with ESP1976.

There is only modest variation in anal cancer incidence rates between cancer networks throughout the UK.[5]

References

  1. Data were provided by the Office for National Statistics on request, July 2015. Similar data can be found here: http://www.ons.gov.uk/ons/rel/vsob1/cancer-statistics-registrations--england--series-mb1-/index.html
  2. Data were provided by ISD Scotland on request, April 2015. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications/index.asp
  3. Data were provided by the Welsh Cancer Intelligence and Surveillance Unit on request, February 2015. Similar data can be found here: http://www.wales.nhs.uk/sites3/page.cfm?orgid=242&pid=59080
  4. Data were provided by the Northern Ireland Cancer Registry on request, march 2015. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/
  5. Anal cancer (C21) European age-standardised incidence rates by UK Cancer Networks, 2008-2010. These data were extracted from the UK Cancer Information Service, version 4.5b 001 on 10/01/2014
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Anal cancer incidence is strongly related to age, with the highest incidence rates generally being in older males and females. In the UK in 2011-2013, on average each year around half (51%) of cases were diagnosed in people aged 65 and over.[1-4]

Age-specific incidence rates rise sharply from around age 35-39, slightly more rapidly for females than males. The highest rates are in the 85-89 (males) and 80-84 (females) age groups. Incidence rates are higher for females than males in most age groups aged 40-44 and over, and this gap is widest at age 45-49, when male:female ratio of age-specific incidence rates (to account for the different proportions of males to females in each age group) of around 10:22.[1-4]

Anal Cancer (C21), Average Number of New Cases per Year and Age-Specific Incidence Rates per 100,000 population, UK, 2011-2013

References

  1. Data were provided by the Office for National Statistics on request, July 2015. Similar data can be found here: http://www.ons.gov.uk/ons/rel/vsob1/cancer-statistics-registrations--england--series-mb1-/index.html
  2. Data were provided by ISD Scotland on request, April 2015. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications/index.asp
  3. Data were provided by the Welsh Cancer Intelligence and Surveillance Unit on request, February 2015. Similar data can be found here: http://www.wales.nhs.uk/sites3/page.cfm?orgid=242&pid=59080
  4. Data were provided by the Northern Ireland Cancer Registry on request, March 2015. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.
Last reviewed:

Anal cancer incidence rates have increased by 130% in Great Britain since the late 1970s.[1-3] This includes a larger overall increase for females than for males. 

For males, European age-standardised (AS) Open a glossary item incidence rates increased by 65% between 1979-1981 and 2011-2013. For females, rates increased by 191% in this period.

Anal Cancer (C21), European Age-Standardised Incidence Rates, Great Britain, 1979-2013

ASR calculated with ESP2013. Not comparable with ASRs calculated with ESP1976.

Over the last decade in the UK (between 2002-2004 and 2011-2013), anal cancer AS incidence rates have increased by 30% for males and females combined, though this includes an increase of 46% for females, and stable rates for males.[1-4]

Anal Cancer (C21), European Age-Standardised Incidence Rates, UK, 1993-2013

ASR calculated with ESP2013. Not comparable with ASRs calculated with ESP1976.

Anal cancer incidence trends probably reflect changing prevalence of risk factors, with recent incidence trends influenced by risk factor prevalence in years past.

Anal cancer incidence rates have increased overall for males in most of the broad age groups in Great Britain since the 1970s, with particularly large increases in younger males.[1-3] The largest increase has been in males aged 25-49, with rates increasing by 189% between 1979-1981 and 2011-2013. In the 80+ age group, rates have  fluctuated but overall remained stable since the late 1970s.

Anal Cancer (C21), European Age-Standardised Incidence Rates, by Age, Males, Great Britain, 1979-2013

ASR calculated with ESP2013. Not comparable with ASRs calculated with ESP1976.

As with males, anal cancer incidence rates have increased overall for females in all of the broad age groups in females in Great Britain since the late 1970s, with particularly large increases in younger females.[1-3] The largest increase has also been in females aged 25-49, with rates increasing more than six-fold (541% increase) between 1979-1981 and 2011-2013.

Anal Cancer (C21), European Age-Standardised Incidence Rates, by Age, Females, Great Britain, 1979-2013

ASR calculated with ESP2013. Not comparable with ASRs calculated with ESP1976.

References

  1. Data were provided by the Office for National Statistics on request, July 2015. Similar data can be found here: http://www.ons.gov.uk/ons/rel/vsob1/cancer-statistics-registrations--england--series-mb1-/index.html
  2. Data were provided by ISD Scotland on request, April 2015. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications/index.asp
  3. Data were provided by the Welsh Cancer Intelligence and Surveillance Unit on request, February 2015. Similar data can be found here: http://www.wales.nhs.uk/sites3/page.cfm?orgid=242&pid=59080.
  4. Data were provided by the Northern Ireland Cancer Registry on request, March 2015. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.
Last reviewed:

The lifetime risk of developing anal cancer is around 1 in 795 for men and around 1 in 470 for women, in 2012 in the UK.[1]

The lifetime risk for anal cancer has been calculated on the assumption that the possibility of having more than one diagnosis of anal cancer over the course of a lifetime is very low (‘Current Probability’ method).[2]

References

  1. Lifetime risk estimates calculated by the Statistical Information Team at Cancer Research UK. Based on data provided by the Office of National Statistics, ISD Scotland, the Welsh Cancer Intelligence and Surveillance Unit and the Northern Ireland Cancer Registry, on request, December 2013 to July 2014.
  2. Esteve J, Benhamou E and Raymond L. Descriptive epidemiology. IARC Scientific Publications No.128, Lyon, International Agency for Research on Cancer, pp 67-68 1994.
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There is evidence for an association between anal cancer incidence and deprivation for both males and females in England.[1] England-wide data for 2006-2010 show European age-standardised Open a glossary item incidence rates incidence rates are 82% higher for males living in the most deprived areas compared with the least deprived, and 53% higher for females.[1]

Anal Cancer (C21), European Age-Standardised Incidence Rates by Deprivation Quintile, England, 2006-2010

The estimated deprivation gradient in anal cancer incidence between people living in the most and least deprived areas in England has not changed in the period 1996-2010.[1] It has been estimated that there would have been around 150 fewer cancer cases each year in England during 2006-2010 if all people experienced the same incidence rates as the least deprived.[1

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Cancer Statistics Explained

See information and explanations on terminology used for statistics and reporting of cancer, and the methods used to calculate some of our statistics.

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