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Cancer of unknown primary Key Facts

CUP Stats DoughnutKey messages on incidence and mortality and a summary table of the statistics for cancer of unknown primary are given here. 

More comprehensive information and statistics for cancer of unknown primary is here: incidence.

The latest statistics available for cancer of unknown primary are; incidence 2010 and mortality 2010. Source years are specified in the statistics table. Find out why these are the latest statistics available.

What is cancer of unknown primary?

  • Patients are recorded as having cancer of unknown primary (CUP) if the primary site of the cancer cannot be established or the tumour has been registered without specification of site. Some patients diagnosed initially with CUP may then have their primary site determined (either during the diagnostic/treatment process or death) and will leave no trace of their initial diagnosis; other patients with CUP may be incorrectly registered - for example, if a cancer registry does not receive sufficient information to know the site of malignancy, they may be misclassified as CUP.
  • Other patients may be registered as having cancer of unknown primary if they had such advanced disease that they did not go through investigations to find the primary site or where a patient died from cancer and it is clinically irrelevant to ascertain what specific cancer the patient died from.

section reviewed 14/01/13
section updated 19/07/12

How common is cancer of unknown primary?

Read more in-depth cancer of unknown primary incidence statistics.

section reviewed 14/01/13
section updated 14/01/13

How many people die from cancer of unknown primary?

  • In 2010 in the UK, there were around 10,500 deaths from cancer of unknown primary.

section reviewed 22/02/13
section updated 19/07/12

Cancer of unknown primary statistics table

CANCER OF UNKNOWN PRIMARY STATISTICS Males Females Persons Country Year3
Number of new cases per year 4,415 5,170 9,585 UK 2010
Incidence rate per 100,000 population1 10.9 9.7 10.2
Number of deaths per year2 4,815 5,657 10,472          UK             2010  
Mortality rate per 100,000 population1 11.6 10.1 10.7

1. European age-standardised     2. Deaths can be higher than cases because of how the data is recorded    
3. Latest statistics available

More detailed cancer of unknown primary incidence statistics can be found using this link: incidence.

section reviewed 22/02/13
section updated 14/01/13

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