Secondary breast cancer
Secondary breast cancer means that a cancer that began in the breast has spread to another part of the body. It is also called advanced or metastatic breast cancer.
Breast cancer can spread to any part of the body. But most commonly spreads to the:
bones
liver
lungs
brain
The general symptoms of secondary breast cancer include:
tiredness (fatigue)
difficulty sleeping
loss of appetite
unexplained weight loss
feeling or being sick
pain
Bone pain is the most common symptom of breast cancer that has spread to the bones. Your bones might also become weaker and more likely to break (fracture).
Sometimes when bones are damaged by advanced cancer, the bones release calcium into the blood. This is called hypercalcaemia and can cause various symptoms such as:
tiredness
feeling sick (nausea)
constipation
irritability
confusion
thirst
Find out more about cancer that has spread to the bones
Breast cancer can spread to the bones in the spine causing pressure on the spinal cord. The pressure can stop the nerves from working normally. This is called spinal cord compression.
Back pain is usually the first symptom of spinal cord compression.
Spinal cord compression is an emergency. You should contact your treatment team immediately if you are worried you might have spinal cord compression.
Find out more about the symptoms and treatment of spinal cord compression
You may have any of the following symptoms if cancer has spread to your liver:
tiredness
pain on the right side of your tummy (abdomen) where the liver is
feeling sick (nausea)
loss of appetite
a swollen abdomen
yellowing of the skin and whites of the eyes (jaundice)
itchy skin
Find out more about cancer that has spread to the liver
You may have any of these symptoms if your cancer has spread into the lungs:
a cough that doesn’t go away
shortness of breath
ongoing chest infections
chest pain
coughing up blood
a build up of fluid between the chest wall and the lung (a pleural effusion)
Find out about cancer that has spread to the lungs
Cancer that has spread to the brain can cause different symptoms depending on where in the brain it spreads to. You might have any of these symptoms:
headaches
weakness or numbness in your limbs
memory problems
behaving in a way that is unusual for you
feeling or being sick
seizures (fits)
changes to your eyesight such as loss of sight (vision)
confusion and difficulty understanding
difficulty speaking
Find out more about cancer that has spread to the brain
You might have treatments such as:
chemotherapy
radiotherapy
targeted drugs
hormone therapies
These might shrink the cancer and help to control any symptoms you have.
Find out about treatment for secondary breast cancer
There are symptom control teams in most cancer units. They can help you to stay as well as possible for as long as possible. They are also in hospices and many general hospitals.
Most symptom control teams have home care services so they can visit you at home.
Find out about controlling symptoms of secondary breast cancer
When breast cancer is advanced it can't be cured. But treatment can control it for some time and help to relieve symptoms.
Finding out that you can’t be cured is distressing and can be a shock. It’s common to feel uncertain and anxious. It's normal to not be able to think about anything else.
Lots of information and support are available to you, your family, and friends. It can help to find out more about your cancer and the treatments you might have. Many people find that knowing more about their situation can make it easier to cope.
Talk to your doctor or nurse to understand:
what your diagnosis means
what is likely to happen
what treatment is available
how treatment can help you
You and your family will be looked after by a team of people who can provide you with support and information.
Last reviewed: 20 Jul 2023
Next review due: 20 Jul 2026
Secondary breast cancer is also known as advanced or metastatic breast cancer. Locally advanced breast cancer is different from secondary breast cancer. You have tests such as a biopsy and a CT scan to help diagnose secondary breast cancer.
There are different types of breast cancer and breast conditions, including breast cancer in men, and conditions related to breast cancer. Find out more about the different types.
You have a number of tests to check for breast cancer. This includes a breast examination, a mammogram, a biopsy and scans.
There is support to help you cope with the emotional, practical and physical issues you might have when you have secondary breast cancer. Find out more.
The aim of treatment for secondary breast cancer is to control the cancer, relieve the symptoms and maintain your quality of life. Treatments such as chemotherapy or radiotherapy can help to reduce symptoms and might make you feel better.
Find out about breast cancer, including symptoms, diagnosis, treatment, survival, and how to cope with the effects on your life and relationships.

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