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Read about screening for persistent trophoblastic disease (PTD) and choriocarcinoma.

What persistent trophoblastic disease and choriocarcinomas are

Persistent trophoblastic disease and choriocarcinomas belong to a group of pregnancy related tumours known as gestational trophoblastic disease (GTD).

Persistent trophoblastic disease occurs in some women after an abnormal pregnancy called a molar pregnancy.

Choriocarcinoma can occur after a normal pregnancy, a molar pregnancy, a miscarriage or a termination of pregnancy (an abortion).

What screening is

Screening means testing people for early stages of an illness before they have any symptoms. For screening to be useful the tests:

  • must be reliable at picking up the illness
  • must be simple and quick
  • overall must do more good than harm to people taking part

Checking for GTD

If you have had a molar pregnancy, you will be under the care of a specialist hospital. You have regular urine tests and blood tests to measure the levels of a hormone called human chorionic gonadotrophin (hCG). These tests pick up persistent trophoblastic disease, usually before you notice any symptoms.

After a miscarriage or abortion, doctors often check the foetus and placenta for any abnormalities and this can pick up signs of molar pregnancy. 

Specialist centres for GTD

In the UK there are 3 specialist hospitals for women with gestational trophoblastic disease. All women diagnosed with any type of GTD are registered at one of these centres for follow up. The centres are at

  • Charing Cross Hospital in London
  • Weston Park Hospital in Sheffield
  • Ninewells Hospital in Dundee

Weston Park Hospital and Charing Cross Hospital are also treatment centres for women who need chemotherapy for persistent trophoblastic disease or choriocarcinoma. 

Information and help

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About Cancer generously supported by Dangoor Education since 2010.