After surgery and radiotherapy in 2012-13, I tried various drugs in 2013, anastrazole, tamoxifen and lastly, exemestrane but finally decided, with agreement of my oncologist and surgeon, to come off all of them as I had side-effects with everything. I pursued each for a few months but exemestane was the worst - making me feel dreadful and giving me joint pains and an epulis (swelling on gum) and exascerbating existing gum disease so much that I had to have numerous dental implants. I have had one total knee replacement (2016) but still have bad knee pain in both knees. I came on this site to see if the anti-oestrogen drugs, in particular exemestane, could be responsible for my current symptoms. It has been interesting to read other posts. Just had my regular 18 month mammogram and, hopefully, all seems fine.