Together we will beat cancer


Anyone know anything about Provera (Medroxyprogesterone)

16 Jan 2016 07:53

I know there have been previous discussions about this drug but I wondered if there was anyone currently taking it.

I have incurable cancer which was diagnosed 16 months ago.  It has an average life span of 12-14 months so I am pretty nervous.  I have always refused radio and chemotherapy and relied on an immune system that I have built up over 71 years, but I have now been offered Provera.  My cancer, happily, has not spread and is still all contained in my pelvic area, I have a bit of pain but have learnt to take my medication regularly so I can live a fairly normal life again.  My oncologist says Provera has a high rate of blood clots because it makes your blood sticky and am sitting here looking at the box wondering if I should give it a go. Apparently it gives you a huge appetite, too, so I am trying to educate myself into eating low.calorie food and get some more exercise in.Anyone have any thoughts on this?


Anyone know anything about Provera (Medroxyprogesterone)

18 Jan 2016 14:00 in response to Pauline4

Hello Pauline,

I hope others who are taking Provera will be along soon to share their experience with you.

I did a little search for you and found that a few months ago, jenie was also asking on the forum whether she should give Provera a go or not. You can read her thread here and perhaps you could drop her a line and ask her, for example, what decision she took in the end?

We have an information page on Provera here  which I hope you will find helpful. Feel free to give our nurses a call too to talk it through with them on this free number 0808 800 4040, Monday to Friday, 9am to 5pm.

Very best wishes,


Anyone know anything about Provera (Medroxyprogesterone)

18 Jan 2016 14:47 in response to Moderator Lucie

Thank you so much for the information, Lucie.  I think that it has made my mind up.  I am not good at taking medication unless I know it has minimal side effects and this drug seems to have more than its share.  Although my cancer is incurable I have managed for 18 months and have just been told there is no spread and it is still all contained in my pelvic area.  Think I will take my chances on doing nothing!

Anyone know anything about Provera (Medroxyprogesterone)

18 Jan 2016 15:31 in response to Pauline4

Hi Pauline

I hope you don’t mind me chipping in but moderator Lucie thought I might have something to add.  It would be good to talk things through with your doctor before deciding not to take anything that has been prescribed for you.  It is your choice to decide what to do and what you feel would be right for you, but it is hard to predict how you will react to any medicine.  Some people taking this drug have very few problems with it while others may have more.  It is worth remembering that once you start taking any drug you can always discuss with your doctor discontinuing it or changing it if you do experience side effects, and most side effects will stop once you stop taking the drug.

I hope that helps


Anyone know anything about Provera (Medroxyprogesterone)

18 Jan 2016 15:58 in response to CRUK Nurse Martin

Thanks, Martin.  It would seem the side effects are very numerous abd some quite common.  My oncologist knows how I feel about drugs but stressed the problems with blood clots, saying that Provera made your blood sticky.  He said I would get a huge almost uncontrollable appetite and would need to exercise more.  I am already a couple of stone overweight and struggling to lose it and exercise is very difficult. due to a constant cough. I feel he would understand if I decided against it.  He has already told me I am past my 'sell-by' date so anytime is a bonus.  Happy