Talk to your Oncologist and/or your GP, the night sweats may be a side effect of your medication and you may need something to take the edge off your natural anxiety to help you get off to sleep.

You'd be unusual if you didn't get tired and irritable whilst on chemo :-)

You should have a contact number for the Oncology team, usually a named/lead specialist nurse, who you can tell about any side effects. If necessary, they'll liaise with your Oncologist. Mine was great in helping me change my anti-nausea and anti-constipation medication (oops TMI?).