Starting injections for ovarian suppression

Hi there

I have breast cancer, completed 6 cycles of chemo, 15 of radiotherapy and I'm about to start the long term treatments. I will be having either Leuprorelin or Goserelin but I still don't know which one. I know that the first one is every 3 months and second one every month. I have needle phobia so I would rather do this every 3 months but I'm scared it might not be as effective. Is there anyone who had any one of these injections? I'm concerenced about where and how they are administered, how long they take and whether one has more side effects than the other. (My chemotherapy was one of the worst regarding side effects and I'm too reluctant to do anything intravenous now). If anyone knows what is the difference between them and their effectiveness it would be a help. I have an appointment with my oncologist and I'll be bringing all these questions with me but I just want to feel more in control now so when I have to decide I know my decision is not phobia driven.

Thank you

  • Hi Eirwyn and thanks for posting.  I'm sorry to hear about your situation.

    Goserelin and Leuprorelin are both hormone therapies, given by an injection into your tummy, buttocks or your thigh.  The hormones then take effect over  a number of weeks or months.  The injections don't normally hurt but can feel a bit achy or itchy afterwards.  We have information about both of these on our website, you can read about side effects and how to manage them too. Follow this link for the Goserelin information, and this one to find out about Leuprorelin.

    Side effects can be different for everyone, so one person may experience lots, while someone else having the same treatment may not have any at all.  Some people find that they decrease over time, but the only way to know how you will feel is by having the treatment.

    It is a great idea to write questions down to take to your next appointment, once you have read through the information you may find you have more, and your oncologist may recommend one treatment over the other.

    I wonder if it might be an idea to try some techniques to help your needle phobia.  There are some tips here that you might find useful.

    You have posted in the ask the nurses section, you may find that more people who have had the treatment would respond if you post in another section too.

    Please get back to us if you need any more information or support.  You might like to talk things through with one of the nurses on our helpline.  The number to call is Freephone 0808 800 4040 and the lines are open from 9am till 5pm Monday to Friday.

    Take care,

    Rachel