Hi Lisa, yes everything your telling us is exactly like me. I saw a skin care nurse on Monday, she was the one that organised my morphine gell, she did have a look at my bottom , cause no one had checked it since I started treatment. She told me what to expect as treatment goes on, she gave me loads of Diprobase which I use all the time and I don't have to wash that off before treatment. She also gave me a potty which I love, it is lovely just to sit your bum in warm water. The itching hasn't been too bad for the last 2 days, and my bowels are not the same. I go every day, my poo is small and narrow, and I don't just go and get of the toilet, I can spend 15 minutes at a time on the loo. After my surgery I was left with 2 small skin tags, these are now swollen and feel like troublesome piles, hopefully they will shrink again. I don't think they should be telling you to persevere with any pain. As soon as I've mentioned something going on they have been there to help. Even in chemo today I mentioned I had a bad evening last Saturday when my temp went up and I felt unwell but it only lasted about an hour, I was told today if that happens again I'm to get in touch with the hospital.