Adjuvant chemotherapy for Uterine Cancer

Hello, I was diagnosed with Endometrial Cancer in March 2020 and underwent Open Abdominal Hysterectomy. I start Radiotherapy 18th May, 25 sessions over 5 weeks Mon-Fri. I will then have 2 sessions of brachytherapy. My final diagnosis was Stage 2, Grade 3. My Consultant has discussed Adjuvant Chemotherapy to follow and I am trying to weigh up the pros and cons of  that. I would be grateful to receive any advice from someone in a similar situation.

 

Many thanks

  • Hi Millsy61, I was also diagnosed with endometrial cancer in Dec 2019 and underwent a radical hysterectomy in Jan 2020. I too was Stage 2 Grade 3. My consultant recommended 6 chemotherapy, 25 radiotherapy and 2 brachytherapy in that order. Unfortunately after only one chemotherapy I had to stop.  I am. now halfway through my radiotherapy treatments. I am interested to hear that you are having radio and brachy before chemo or did I get the wrong end of the stick?  I think if we are grade 3 they like to do the belts and braces approach, I was really scared of having chemo but once they told me I wasnt getting any more, I wanted to have it!  I do believe that if a treatment is recommended then there is a reason for it.  But everyone is different.  I have been scared before starting every step, but once started , the fear disappears somewhat, and I cannot wait to get to the end of treatment.  I can do this. You can do this. We can do this.x

  • Thanks catswhiskers, yes, it is Radiotherapy, brachy followed by Chemo for me   I just have a gut feeling about the Chemo and have done the research. Just not sure I want to do it. Good luck to you going forward.

  • Hi Millsy61, thanks fir your reply.  Hope you are recovering well from your op.  I wasnt given the option about the order the treatment was in so I find this really interesting.  Did they say which chemo you would be having?  

  • Hi catswhiskers. Recovering well from Operation thank you.I asked Consultant to get details of the Chemo for me and we will meet on the 22nd after my first week of Radiotherapy. I think she said it was a combination of two. I will let you know how I get on next week.

  • Hi Millsy61, glad to hear you are recovering well.  Be nice to hear how you are getting on. x

  • Hi catswhiskers, hope I find you well today. Finished my 1st week of radiotherapy on Friday and so far so good, bit of upset tummy but am thinking it may just be nerves and Iam having to travel into London each day on train and tube, Covid worries and all that stuff. I found out the drug combination for Chemo would be Paclitaxel and Cisplatin. Did you have to stop because of side effects? 

    A bit more info on me may give you a clearer idea of why I am hesitant to undergo chemo. I am 61 with a small family network, I am divorced with no children. I work full time and need to continue to do so. I am also  very aware of what Chemo can do long term to your health with all the side effects it carries. I have been told that I have a 20% chance of recurrence, which with the Chemo would reduce this number down by a further 3 to 5%. Only I can make a decision, but just want to make sure I am covering all the angles on this.x

  • Hey Millsy61, nice to hear from you.  So glad your furst week of radio went well.  The disrrhoea is psr for the course so unless it is extreme you wont need to take anything, just start cutting out certain fruit veg and start eating white bread.  They will probably give you a diet sheet.  My chemo was carboplatin/paclitaxel.  Within about 3 minutes I had a reaction - they said it was an allergic reaction to the compound.  They continued the chemo feeding it in much more slowly so I was there for 10 hours from start to finish,  unfortunately my bloods showed up reduced kidney function and I was hospitalised twice for fluids to build myself up fir next chemo but it jyst wasnt happening,mand my chemo couldnt continue so about a month later I started radiotherapy.  My consultant told me it was a 40% chance of recurrence, the chemo/radio would reduce this by 10% so still very very high.  Your figures are much lower for same stage/grade as me so I must be different.  I do know that I had more than 50% muscle invasion so maybe that is why.  So long as you have all the information only you can make the decision about what treatment to have. Its you who is going to have to go through it, your body so your choice.  Im here if you need anything. X

  • Thanks catswhiskas, hope you enjoy the weekend.x