Professor Nicholas Coleman

Getting to the roots of cervical cancer

Through his group’s research at our Cambridge Cancer Centre, Professor Nicholas Coleman wants to better understand how cervical cancer develops in order to find new ways to tackle the disease.

Virtually all cases of cervical cancer are caused by infection with the human papilloma virus. There are lots of different types of this virus, but only some are capable of causing cancer. Professor Coleman is studying cells in a dish and patient samples to find out more about how these ‘high-risk’ viruses cause cervical cancer. In particular, his group is focussing on the genetic and molecular changes they trigger that underlie disease development.

Researchers and doctors will then be able to use this information to improve how they identify faulty cervical cells that could go on to become cancer in women. It might also help them develop drugs that target the molecules and genes that go wrong in this disease. Ultimately, by helping to improve the detection and treatment of this disease, this work will hopefully lead to more people surviving cervical cancer. 


Cervical cancer
Cancer aetiology
Cancer biology

Department of Pathology, Tennis Court Road, Cambridge