Current research into immunotherapies
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Saving lives through research
From finding new ways to galvanise the immune system to developing new immunotherapy drugs, we're working to get new, effective treatments to patients. Below are some examples of what our researchers are doing right now.
Our current researchers
Using cancer-fighting viruses
In London, Dr Michelle Lockley is studying high grade serous cancer, the most common type of ovarian cancer. She’s looking at the best way to use cancer-fighting viruses as a treatment for the disease. She hopes to identify drugs that increase the power of these viruses, especially in cases of ovarian cancer where treatment no longer works.
The immune system and pancreatic cancer
Professor Paul Moss in Birmingham is studying the role our body’s immune system plays in pancreatic cancer. He is interested in how pancreatic cancer cells stop immune cells from finding and destroying them. He also wants to know the impact this has on how well new treatments like immunotherapy work.
Killing cancer cells
Dr Stephen Tait in Glasgow is working on a way to kill cancer cells that helps the immune system recognise the rest of the cancer cells. He believes if the immune system is armed against the tumour, combining this way of killing cancer cells with immunotherapy drugs could be a really effective way to tackle the disease.
Stripping away cancer's disguise
Dr Alison Taylor in Leeds is investigating new experimental drugs which may stop cancer cells being masters of disguise. By developing a way to take off cancer's 'invisibility cloak', she believes this could to help the immune system recognise and kill cancer cells and lead to new immunotherapies in the future.
Stopping cancer cells from communicating
In Manchester, Dr Claus Jorgensen is studying how pancreatic cancer cells ‘talk’ to the cells around them and to the body’s immune system. His work looks at how genetic faults in pancreatic tumours cause changes in how these cells talk. Understanding and interfering with this communication could lead to new treatments.