
"I am glad that taking part in a trial might help others on their own cancer journey.”
Please note - this trial is no longer recruiting patients. We hope to add results when they are available.
This study is looking at cells that have broken away from as a possible way of monitoring treatment for womb (endometrial) cancer, and the most common type of ovarian cancer called epithelial ovarian cancer.
Cancers need a blood supply to help them grow and survive. So growing cancers encourage the growth of new blood vessels. This is called angiogenesis. Blood vessels are lined with cells called endothelial cells. When these cells are damaged, they are released into the bloodstream, and become circulating endothelial cells (CECs). Researchers have found increased numbers of CECs in people with cancer, which may be a sign (biomarker) that new blood vessels are being formed.
Researchers in this study would like to find out more about how chemotherapy affects these cells. They will collect blood samples and medical information from women having chemotherapy for these cancers. They will count the numbers of CECs, and another type of endothelial cell from the called circulating endothelial progenitors (CEPs). They will also study the makeup of sugars in the bloodstream linked to CECs and CEPs.
You will not have any direct benefit from taking part in this study, and it is unlikely to change your treatment plan in any way. But the results of the study will be used to help people with cancer in the future.
You can enter this study if you
You cannot enter this study if you
This study will recruit 200 women. Everyone taking part will give up to 2 blood samples before they start chemotherapy, and one sample during their course of chemotherapy.
You will also give permission for the team to store these blood samples to use both now and in future research. And to collect information from your medical notes including about your cancer, treatment and test results.
Where possible, you will give your study blood samples when you are already at the hospital for your treatment. So you should not need to make any extra visits to take part in this study.
You may have a small bruise where you gave your blood sample.
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Professor Gordon Jayson
Experimental Cancer Medicine Centre (ECMC)
NIHR Clinical Research Network: Cancer
The Christie NHS Foundation Trust
If you have questions about the trial please contact our cancer information nurses
Freephone 0808 800 4040
"I am glad that taking part in a trial might help others on their own cancer journey.”