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Treatment for stomach cancer

9 Jun 2019 17:14



Hi everyone! I was diagnosed with stage 4 adenocarcenoma of the stomach in Jan 2019 and underwent 3 rounds of Folfox chemotherapy, and total gastrectomy 6 weeks ago. My oncologist has given me the option of further chemotherapy if I want it although I suffered quite severe side effects and tumour response was minimal. I also understand that there is a high risk of recurrence. I have read about targeted therapy and immunotherapy but these aren’t being offered. Does anyone have knowledge or experience of these treatments or of alternative chemotherapy drugs which may be used as an alternative? Many thanks

Treatment for stomach cancer

11 Jun 2019 12:36 in response to Feather057

Hello Feather and thanks for posting, 

I hope you are recovering ok after your surgery and managing to get some food down, I expect it is a case of little and often.

Treatment recommendations are based on evidence and at the moment targeted and immune therapies aren't a standard addition to surgery for stomach cancer.  Perioperative (pre- and post-operative) chemotherapy is the standard treatment approach and I'm afraid I don't know of a proven alternative. 

There is one targeted treatment, Herceptin, that can be used in stomach cancer, but only for people whose cancers are the right match and have the target (HER 2) protein that the drug was designed to block and who also have advanced disease.  Immunotherapy medicines are still being researched in several cancers, including stomach cancer and in different contexts, but for now they don't have a role in treatment alongside surgery for stomach cancer.  

There is an ongoing UK trial trying to find out if adding aspirin after stomach cancer surgery could help to prevent the cancer from coming back. You can read about this on our trials database at this link.  If you are interested in taking part, talk to your specialist. 

I can appreciate that it is hard to contemplate more chemotherapy after having quite severe side effects last time. Treatment decisions like these are difficult, so do talk it over as much as you need to with your specialist team.

Give us a call if you want to talk things through.  The number to call is Freephone 0808 800 4040 and the lines are open from 9am till 5pm Monday to Friday.

Take care, 


Treatment for stomach cancer

12 Jun 2019 08:56 in response to CRUK Nurse Julia

Many thanks for your response Julia. I shall definitely look into the Add Aspirin trial. Also just to let you know, I think this is a brilliant resource and facility for cancer sufferers and their families, I wish I had looked into using it sooner. Best wishes to you and all the team,