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Our research into cancer biology

All cancers develop as a result of uncontrolled growth of cells in the body. This loss of control is caused by the accumulation of faults or mutations in important genes including oncogenes and tumour suppressor genes.

Cancer Research UK-funded scientists are at the forefront of studying the biology of cancer cells. They have already made tremendous contributions to this area through investigating key genes and proteins, including p53, BRAF and APC.

Our researchers continue to investigate how these faulty molecules work together to promote cancer development. This work is essential for improving our understanding of cancer and will form the basis for developing new ways to prevent, diagnose and treat different forms of the disease.

Below are some of the highlights of our cancer biology research portfolio.

Researcher listing

78 researchers found. Filter results:
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Researcher David Adams profile image
David Adams

Searching for early signs of cancer
Experimental Mouse Genetics

Wellcome Trust Sanger Institute

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Holger Auner

Killing myeloma cells with toxic waste
MRC Clinical Sciences Centre

Imperial College London

Photo of Shankar Balasubramanian
Shankar Balasubramanian

Solving molecular puzzles

Cancer Research UK Cambridge Institute

Researcher Alison Banham profile image
Alison Banham

Antibodies to shut off the blood supply
Nuffield Department of Clinical Laboratory Sciences

University of Oxford

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Francis Barr

Splitting up - understanding how cancer cells divide
Department of Biochemistry

University of Oxford

Researcher Buzz Baum profile image
Buzz Baum

The shape of things to come
Laboratory for Molecular Cell Biology

University College London

Researcher Richard Bayliss profile image
Richard Bayliss

Stopping cancer cells getting out of control
Department of Biochemistry

University of Leicester

Researcher Julian Blow profile image
Julian Blow

How do cells copy their DNA accurately?

University of Dundee

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Robert Brown

'Epigenetics' and the problem of drug resistance
Department of Surgery and Cancer

Imperial College London

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Cristina Lo Celso

Fighting for space – studying stem cells in leukaemia
Center for Regenerative Medicine

Imperial College London

Researcher Spencer Collis profile image
Spencer Collis

Department of Oncology

University of Sheffield

LRI researcher Vincenzo Costanzo profile image
Vincenzo Costanzo

London Research Institute

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Ana Cvejic

Searching for leukaemia genes
Department of Haematology

University of Cambridge

LRI researcher John Diffley profile image
John Diffley

Finding out how cells divide

London Research Institute

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Albena Dinkova-Kostova

Protecting our cells from sun damage
Division of Cancer Research

University of Dundee

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Anne Donaldson

Using yeast cells to understand cancer
Institute of Medical Sciences

University of Aberdeen

LRI researcher Julian Downward profile image
Julian Downward

Understanding how communication goes wrong in cancer cells
Signal Transduction Lab

London Research Institute

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Viji Draviam

University of Cambridge

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Tariq Enver

Targeting rogue stem cells in childhood leukaemia
UCL Cancer Institute

University College London

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Gerard Evan

Understanding a key cancer driver
Department of Biochemistry

University of Cambridge

Researcher Michaela Frye profile image
Michaela Frye

Studying skin stem cells
University of Cambridge

University of Cambridge

LRI researcher Holger Gerhardt profile image
Holger Gerhardt

Fixing the plumbing – studying tumour blood vessels

London Research Institute

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David Glover

Building the scaffolding for cell division
Department of Genetics

University of Cambridge

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Anthony Green

Finding new treatments for blood cancers

University of Cambridge

Researcher Adrian Harris profile image
Adrian Harris

Targeting a cancer's blood supply
Weatherall Institute of Molecular Medicine

University of Oxford

LRI researcher Caroline Hill profile image
Caroline Hill

The two faces of TGF beta
Room 406

London Research Institute

Researcher Helfrid Hochegger profile image
Helfrid Hochegger

Understanding how cancer cells divide
Radiation Genetics

University of Sussex

Researcher Kairbaan Hodivala-Dilke profile image
Kairbaan Hodivala-Dilke

Targeting blood vessel growth for cancer treatment
Centre for Tumor Biology

Queen Mary, University of London

Researcher Tessa Holyoake profile image
Tessa Holyoake

Targeting leukaemia at its roots
Paul O'Gorman Leukaemia Research

University of Glasgow

Researcher Danny Huang profile image
Danny Huang

How signals go wrong in cancer

Cancer Research UK Beatson Institute

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Updated: 17 September 2009