Peter Sasieni publications

Why young women should be screened for cervical cancer: the distinction between CIN2 and CIN3 Response
Sasieni P;Castanon A;Parkin MD
Int J Cancer 2010; 126 (9):2257-2258.
DOI: 10.1002/ijc.24785.

Has cytology become obsolete as a primary test in screening for cervical cancer?
Sasieni P
J Med Screen 2010; 17 (1):2-3.
DOI: 10.1258/jms.2010.010010.

Image cytometry accurately detects DNA ploidy abnormalities and predicts late relapse to high-grade dysplasia and adenocarcinoma in Barrett's oesophagus following photodynamic therapy
Dunn JM;Mackenzie GD;Oukrif D;Mosse CA;Banks MR;Thorpe S;Sasieni P;Bown SG;Novelli MR;Rabinovitch PS;Lovat LB
Br J Cancer 2010; 102 (11):1608-1617.
DOI: 10.1038/sj.bjc.6605688.

Predicted impact of vaccination against human papillomavirus 16/18 on cancer incidence and cervical abnormalities in women aged 20-29 in the UK
Cuzick J;Castanon A;Sasieni P
Br J Cancer 2010; 102 (5):933-939.
DOI: 10.1038/sj.bjc.6605528.

ACOG guidelines on cervical screening: a step in the right direction
Sasieni P;Castanon A;Cuzick J
J Med Screen 2010; 17 (2):55-56.
DOI: 10.1258/jms.2010.010054.

Effectiveness of cervical screening with age: population based case-control study of prospectively recorded data
Sasieni P;Castanon A;Cuzick J
BMJ 2009; 339 ():b2968.
UKPubMed (open access);  PubMed;  DOI: 10.1136/bmj.b2968.

How many cervical cancers are prevented by treatment of screen-detected disease in young women?
Sasieni P;Castanon A;Parkin DM
Int J Cancer 2009; 124 (2):461-464.
PubMed;  DOI: 10.1002/ijc.23922.

Is the recent fall in incidence of post-menopausal breast cancer in UK related to changes in use of hormone replacement therapy?
Parkin DM
Eur J Cancer 2009; 45 (9):1649-1653.
PubMed;  DOI: 10.1016/j.ejca.2009.01.016.

Further analysis of the ARTISTIC trial
Sasieni P;Castle PE;Cuzick J
Lancet Oncol 2009; 10 (9):841-842.

Screening and adenocarcinoma of the cervix
Sasieni P;Castanon A;Cuzick J
Int J Cancer 2009; 125 (3):525-529.
PubMed;  DOI: 10.1002/ijc.24410.

A deterministic model for estimating the reduction in colorectal cancer incidence due to endoscopic surveillance
Cafferty FH;Sasieni PD;Duffy SW
Stat Methods Med Res 2009; 18 (2):163-182.

The potential for prevention of colorectal cancer in the UK
Parkin DM;Olsen AH;Sasieni P
Eur J Cancer Prev 2009; 18 (3):179-190.
PubMed;  DOI: 10.1097/CEJ.0b013e32830c8d83.

Sun exposure and melanoma risk at different latitudes: a pooled analysis of 5700 cases and 7216 controls
Chang YM;Barrett JH;Bishop DT;Armstrong BK;Bataille V;Bergman W;Berwick M;Bracci PM;Elwood JM;Ernstoff MS;Gallagher RP;Green AC;Gruis NA;Holly EA;Ingvar C;Kanetsky PA;Karagas MR;Lee TK;Le Marchand L;Mackie RM;Olsson H;Osterlind A;Rebbeck TR;Sasieni P;Siskind V;Swerdlow AJ;Titus-Ernstoff L;Zens MS;Newton-Bishop JA
Int J Epidemiol 2009; 38 (3):814-830.
UKPubMed (open access);  PubMed;  DOI: 10.1093/ije/dyp166.

Primary endpoints for randomised trials of cancer therapy
Cuzick J
Lancet 2008; 371 (9631):2156-2158.

Predicting the impact of the screening programme for colorectal cancer in the UK
Parkin DM;Tappenden P;Olsen AH;Patnick J;Sasieni P
J Med Screen 2008; 15 (4):163-174.

Chemoprevention of breast cancer.
Cuzick J
Breast Cancer 2008; 15 (1):10-16.
PubMed;  DOI: 10.1007/s12282-007-0006-z.

Gene-related cancer spectrum in families with hereditary non-polyposis colorectal cancer (HNPCC)
Geary J;Sasieni P;Houlston R;Izatt L;Eeles R;Payne SJ;Fisher S;Hodgson SV
Fam Cancer 2008; 7 (2):163-172.

The psychosocial impact of human papillomavirus testing in primary cervical screening - a study within a randomized trial
Kitchener HC;Fletcher I;Robert C;Wheeler P;Almonte M;Maguire P
Int J Gynecol Cancer 2008; 18 (4):743-748.

Cancer mortality in the United Kingdom: projections to the year 2025
Olsen AH;Parkin DM;Sasieni P
Br J Cancer 2008; 99 (9):1549-1554.
UKPubMed (open access);  PubMed;  DOI: 10.1038/sj.bjc.6604710.

Relationship between quantitative estrogen and progesterone receptor expression and human epidermal growth factor receptor 2 (HER-2) status with recurrence in the arimidex, tamoxifen, alone or in combination trial
Dowsett M;Allred C;Knox J;Quinn E;Salter J;Wale C;Cuzick J;Houghton J;Williams N;Mallon E;Bishop H;Ellis I;Larsimont D;Sasano H;Carder P;Cussac AL;Knox F;Speirs V;Forbes J;Buzdar A
J Clin Oncol 2008; 26 (7):1059-1065.

Long-term follow-up of cervical abnormalities among women screened by HPV testing and cytology - results from the Hammersmith study
Cuzick J;Szarewski A;Mesher D;Cadman L;Austin J;Perryman K;Ho L;Terry G;Sasieni P;Dina R;Soutter WP
Int J Cancer 2008; 122 (10):2294-2300.
PubMed;  DOI: 10.1002/ijc.23339.

HPV triage for low grade (L-SIL) cytology is appropriate for women over 35 in mass cervical cancer screening using liquid based cytology
Ronco G;Cuzick J;Segnan N;Brezzi S;Carozzi F;Folicaldi S;Palma PD;Del Mistro A;Gillio-Tos A;Giubilato P;Naldoni C;Polla E;Iossa A;Zorzi M;Confortini M;Giorgi-Rossi P;NTCC working grp
Eur J Cancer 2007; 43 (3):476-480.

Cervical cancer prevention and hormonal contraception
Sasieni P
Lancet 2007; 370 (9599):1591-1592.

Phenocopies in families seen by cancer geneticists
Sasieni P
J Med Genet 2007; 44 (6):e82.

Replication timing profile reflects the distinct functional and genomic features of the MHC class II region
Takousis P;Johonnett P;Williamson J;Sasieni P;Warnes G;Forshew T;Azuara V;Fisher A;Wu PJ;Jones T;Vatcheva R;Beck S;Sheer D
Cell Cycle 2007; 6 (19):2393-2398.

Accuracy of liquid based versus conventional cytology: overall results of new technologies for cervical cancer screening: randomised controlled trial
Ronco G;Cuzick J;Pierotti P;Cariaggi MP;Dalla Palma P;Naldoni C;Ghiringhello B;Giorgi-Rossi P;Minucci D;Parisio F;Pojer A;Schiboni ML;Sintoni C;Zorzi M;Segnan N;Confortini M;NTCC Working Grp
BMJ 2007; 335 (7609):28-31.

The ATAC trial: the vanguard trial for use of aromatase inhibitors in early breast cancer
Cuzick J
Expert Rev Anticancer Ther 2007; 7 (8):1089-1094.

The impact of new technologies in cervical cancer screening: Results of the recruitment phase of a large randomised controlled trial from a public health perspective
Giorgi-Rossi P;Segnan N;Zappa M;Naldoni C;Zorzi M;Confortini M;Merito M;Cuzick J;Ronco G
Int J Cancer 2007; 121 (12):2729-2734.

Use of luteinising-hormone-releasing hormone agonists as adjuvant treatment in premenopausal patients with hormone-receptor-positive breast cancer: a meta-analysis of individual patient data from randomised adjuvant trials
Cuzick J;Ambroisine L;Davidson N;Jakesz R;Kaufmann M;Regan M;Sainsbury R;LHRH agonists Early Breast Canc Ov
Lancet 2007; 369 (9574):1711-1723.

Feasibility study of adjustment for contamination and non-compliance in a prostate cancer screening trial
Roemeling S;Roobol MJ;Otto SJ;Habbema DF;Gosselaar C;Lous JJ;Cuzick J;Schroder FH
Prostate 2007; 67 (10):1053-1060.

Long-term results of tamoxifen prophylaxis for breast cancer-96-month follow-up of the randomized IBIS-I trial
Cuzick J;Forbes JF;Sestak I;Cawthorn S;Hamed H;Holli K;Howell A;IBIS
J Natl Cancer Inst 2007; 99 (4):272-282.

Chemoprevention of cervical cancer
Sasieni P
Best Pract Res Clin Obstet Gynaecol 2006; 20 (2):295-305.

Long-term risk of invasive cervical cancer after treatment of squamous cervical intraepithelial neoplasia
Soutter WP;Sasieni P;Panoskaltsis T
Int J Cancer 2006; 118 (8):2048-2055.

Cervical screening in 20-24-year olds
Sasieni P;Kitchener H;Patnick J;Vessey M
J Med Screen 2006; 13 (2):62-63.

Methodological issues in international comparison of interval breast cancers
Bulliard JL;Sasieni P;Klabunde C;De Landtsheer JP;Yankaskas BC;Fracheboud J
Int J Cancer 2006; 119 (5):1158-1163.

Clinical applications of HPV testing: A summary of meta-analyses
Arbyn M;Sasieni P;Meijer CJLM;Clavel C;Koliopoulos G;Dillner J
Vaccine 2006; 24 (Supp 3):78-89.

Genomic profiling identifies discrete deletions associated with translocations in glioblastoma multiforme.
Mulholland PJ;Fiegler H;Mazzanti C;Gorman P;Sasieni P;Adams J;Jones TA;Babbage JW;Vatcheva R;Ichimura K;East P;Poullikas C;Collins VP;Carter NP;Tomlinson IPM;Sheer D
Cell Cycle 2006; 5 (7):783-791.

A comprehensive study of chromosome 16q in invasive ductal and lobular breast carcinoma using array CGH.
Roylance R;Gorman P;Papior T;Wan Y-L;Ives M;Watson JE;Collins C;Wortham N;Langford C;Fiegler H;Carter N;Gillett C;Sasieni P;Pinder S;Hanby A;Tomlinson I
Oncogene 2006; 25 (49):6544-6553.

Mitochondrial DNA mutations are established in human colonic stem cells, and mutated clones expand by crypt fission.
Greaves LC;Preston SL;Tadrous PJ;Taylor RW;Barron MJ;Oukrif D;Leedham SJ;Deheragoda M;Sasieni P;Novelli MR;Jankowski JAZ;Turnbull DM;Wright NA;McDonald SAC
Proc Natl Acad Sci U S A 2006; 103 (3):714-719.

Liquid-based versus conventional cervical cytology
Sasieni P;Fielder H;Rose B
Lancet 2006; 367 (9521):1481-1481.

A multicentre epidemiological study on sunbed use and cutaneous melanoma in Europe
Bataille W;Boniol M;De Vries E;Severi G;Brandberg Y;Sasieni P;Cuzick J;Eggermont A;Ringborg U;Grivegnee AR;Coebergh JW;Chignol MC;Dore JF;Autier P
Eur J Cancer 2005; 41 (14):2141-2149.

Prevention of colorectal cancer by colonoscopic surveillance in individuals with a family history of colorectal cancer: 16 year, prospective, follow-up study
Dove-Edwin I;Sasieni P;Adams J;Thomas HJW
BMJ 2005; 331 (7524):1047-1049.

Promyelocytic leukemia nuclear bodies associate with transcriptionally active genomic regions.
Wang J;Shiels C;Sasieni P;Wu PJ;Islam SA;Freemont PS;Sheer D
J Cell Biol 2004; 164 (4):515-526.
UKPubMed (open access); 

Lower protection of cytological screening for adenocarcinomas and shorter protection for younger women: the results of a case-control study in Florence
Zappa M;Visioli CB;Ciatto S;Iossa A;Paci E;Sasieni P
Br J Cancer 2004; 90 (9):1784-1786.

Reply: The value of case-control audits of screening
Sasieni P;Adams J;Cuzick J
Br J Cancer 2004; 90 (5):1109-1110.

Exposure to the sun and sunbeds and the risk of cutaneous melanoma in the UK: a case-control study
Bataille V;Winnett A;Sasieni P;Newton Bishop JA;Cuzick J
Eur J Cancer 2004; 40 (3):429-435.

Increased risk of skin cancer associated with the presence of epidermodysplasia verruciformis human papillomavirus types in normal skin
Harwood CA;Surentheran T;Sasieni P;Proby CM;Bordea C;Leigh IM;Wojnarowska F;Breuer J;Mcgregor JM
Br J Dermatol 2004; 150 (5):949-957.

Cervical screening in adolescents - at least do no harm
Szarewski A;Sasieni P
Lancet 2004; 364 (9446):1642-1644.

Refining the Amsterdam criteria and Bethesda guidelines: testing algorithms for the prediction of mismatch repair mutation status in the familial cancer clinic.
Lipton LR;Johnson V;Cummings C;Fisher S;Risby P;Eftekhar Sadat AT;Cranston T;Izatt L;Sasieni P;Hodgson SV;Thomas HJW;Tomlinson IPM
J Clin Oncol 2004; 22 (24):4934-4943.

The UK breast-screening programme should start at age 47 years
Sasieni P;Cuzick J
Lancet 2003; 362 (9379):246-247.

Outcomes of screening to prevent cancer - Think of screening as insurance
Sasieni PD
BMJ 2003; 327 (7405):50-50.

Evaluation of the UK breast screening programmes
Sasieni P
Ann Oncol 2003; 14 (8):1206-1208.

Iterated residuals and time-varying covariate effects in Cox regression
Winnett A;Sasieni P
J R Stat Soc B 2003; 65 (Pt 2):473-488.

X-inactivation patch size in human female tissue confounds the assessment of tumor clonality.
Novelli M;Cossu A;Oukrif D;Quaglia A;Lakhani S;Poulsom R;Sasieni P;Carta P;Contini M;Pasca A;Palmieri G;Bodmer W;Tanda F;Wright N
Proc Natl Acad Sci U S A 2003; 100 (6):3311-3314.

Martingale difference residuals as a diagnostic tool for the Cox model
Sasieni PD;Winnett A
Biometrika 2003; 90 (4):899-912.

How many mutations in a cancer?
Tomlinson I;Sasieni P;Bodmer W
Am J Pathol 2002; 160 (3):755-758.

Adjusted Nelson-Aalen estimates with retrospective matching
Winnett A;Sasieni P
J Am Stat Assoc 2002; 97 (457):245-256.

A weighted Kaplan-Meier estimator for matched data with application to the comparison of chemotherapy and bone-marrow transplant in leukaemia
Galimberti S;Sasieni P;Valsecchi MG
Stat Med 2002; 21 (24):3847-3864.

Cervical cancer - Could HPV testing become the sole primary cervical screening test?
Sasieni P;Cuzick J
J Med Screen 2002; 9 (2):49-51.

Metal ion binding and the folding of the hairpin ribozyme
Wilson TJ;Lilley DMJ
RNA 2002; 8 (5):587-600.