Cancer cells on the move
Professor Anne Ridley and her team at Kings College London are studying the molecules that control how cancer cells move and spread around the body.
Professor Ridley is focusing on a family of 20 molecules called Rho GTPases that are involved in cell movement. She is working out how Rho GTPases are involved in cancer cell movement and cancer spread, and how they are controlled. Her team is also investigating how breast cancer cells spread to the lungs.
Learning more about how these molecules enable cancer cells to move could lead to the identification of potential targets for future treatments to help stop cancer spreading.
Other research projects by Anne Ridley
Funding period: 01 May 2010 to 30 June 2013
Funding period: 01 January 2013 to 31 December 2017
Funding period: 01 September 2007 to 31 December 2012
p120ctn and P-Cadherin but Not E-Cadherin Regulate Cell Motility and Invasion of DU145 Prostate Cancer Cells
PLoS ONE.2010;5 :e11801
The PI3K p110 alpha isoform regulates endothelial adherens junctions via Pyk2 and Rac1
J Cell Biol.2010;188 :863-876