Anne Ridley : Cancer Research UK
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Anne Ridley

Researcher Anne Ridley profile image

Cancer cells on the move

King's College London
Randall Division of Cell and Molecular Biophysics
New Hunt's House
Guy's Campus
United Kingdom

Tel: 020 7848 6209
Web: Lab website

Professor Anne Ridley and her team at Kings College London are studying the molecules that control how cancer cells move and spread around the body.

Professor Ridley is focusing on a family of 20 molecules called Rho GTPases that are involved in cell movement. She is working out how Rho GTPases are involved in cancer cell movement and cancer spread, and how they are controlled. Her team is also investigating how breast cancer cells spread to the lungs.

Learning more about how these molecules enable cancer cells to move could lead to the identification of potential targets for future treatments to help stop cancer spreading.

Most cancer deaths are caused by metastases, which form when cancer cells detach from primary cancers and spread via the bloodstream to other tissues. Professor Ridley's laboratory is investigating the molecular mechanisms whereby cancer cells become motile and move across endothelial cells lining blood vessels.

Other research projects by Anne Ridley

Science Committee Programme
Funding period: 01 January 2013 to 31 December 2017