New treatments for children with cancer
Great Ormond Street Hospital for Children NHS Trust
Great Ormond Street
Tel: 0207 829 8832
About Darren Hargrave
Dr Darren Hargrave is a childhood cancer specialist at Great Ormond Street Hospital. He’s running an important clinical trial testing a new treatment for children with tumours that have come back after treatment.
This trial is looking at a new drug called AT9283 that switches off a protein called aurora kinase, which drives the growth of cancer cells. Dr Hargrave is finding out how well the drug works, the best doses to give children and whether there are any side effects.
Almost three quarters of children with cancer are now cured, but too many still lose their lives to this disease. Through research, we will find new treatments to help even more children survive in the future.
Other research projects by Darren Hargrave
CRUKD/09/044 A CR-UK/CCLG Phase I paediatric trial of AT9283, a selective aurora kinase inhibitor, in relapsed and refractory solid tumours
Funding period: 01 January 2008 to 31 October 2013