Searching for early signs of cancer
Dr David Adams and his team at the Wellcome Trust Sanger Institute in Cambridge are studying tiny fragments of DNA that collect in cells as they start to grow of control, heading towards cancer. These fragments are useful indicator of the risk of developing cancer.
Dr Adams and his team are using powerful methods that allow them to sift through many thousands of cells quickly and accurately. They can detect the misplaced fragments of DNA present in early stage cancer cells and work out what gene changes caused the problem. They are screening many different types of cells from mice with different genetic backgrounds to find important hallmarks of cancer risk.
Discovering ways of testing whether people are at increased risk of getting cancer might help prevent the disease and improve early detection.
Other research projects by David Adams
High-throughput in vivo screens for the genetic determinants of genomic stability and cancer susceptibility
Funding period: 01 July 2011 to 31 January 2015
Funding period: 01 September 2012 to 31 August 2016
Funding period: 01 April 2012 to 31 March 2018