Vaginal cancer incidence statistics

Cases

New cases of vaginal cancer, 2014, UK

 

Proportion of all cases

Percentage vaginal cancer is of total cancer cases, 2014, UK

 

Age

Peak rate of vaginal cancer cases, 2012-2014, UK

Trend since 1970s

Vaginal cancer incidence rates have decreased since the late 1970s, GB

 

In 2014, there were 254 new cases of vaginal cancer in the UK, accounting for less than 1% of all new cases of cancer in females.[1-4] The crude incidence rate Open a glossary item shows that there are 0.8 new vaginal cancer cases for every 100,000 females in the UK.

The European age-standardised incidence rates Open a glossary item (AS rates) do not differ significantly between the constituent countries of the UK.[1-4]

Vaginal Cancer (C52), Number of New Cases, Crude and European Age-Standardised (AS) Incidence Rates per 100,000 Population, Females, UK, 2014

England Wales Scotland Northern Ireland UK
Cases 199 17 29 9 254
Crude Rate 0.7 1.1 1.1 1.0 0.8
AS Rate 0.7 1.0 1.0 1.1 0.8
AS Rate - 95% LCL 0.6 0.5 0.7 0.4 0.7
AS Rate - 95% UCL 0.9 1.5 1.4 1.8 0.9

95% LCL and 95% UCL are the 95% lower and upper confidence limits Open a glossary item around the AS rate Open a glossary item

For vaginal cancer, like most cancer types, differences between countries largely reflect risk factor prevalence in years past.

References

  1. Data were provided by the Office for National Statistics on request, June 2016. Similar data can be found here: http://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/cancerregistrationstatisticsengland/previousReleases.
  2. Data were provided by ISD Scotland on request, May 2016. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications/.
  3. Data were provided by the Welsh Cancer Intelligence and Surveillance Unit, Health Intelligence Division, Public Health Wales on request, June 2016. Similar data can be found here: http://www.wcisu.wales.nhs.uk.
  4. Data were provided by the Northern Ireland Cancer Registry on request, May 2016. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.

About this data

Data is for: UK, 2014, ICD-10 C52

Last reviewed:

Vaginal cancer incidence is strongly related to age, with the highest incidence rates being in older females. In the UK in 2012-2014, on average each year almost half (48%) of cases were diagnosed in females aged 70 and over.[1-4]

Age-specific incidence rates rise sharply from around age 45-49, and peak in the 90+ age group.[1-4]

Vaginal Cancer (C52), Average Number of New Cases per Year and Age-Specific Incidence Rates per 100,000 Population, Females, UK, 2012-2014

For vaginal cancer, like most cancer types, incidence increases with age. This largely reflects cell DNA damage accumulating over time. Damage can result from biological processes or from exposure to risk factors. A drop or plateau in incidence in the oldest age groups often indicates reduced diagnostic activity perhaps due to general ill health.

References

  1. Data were provided by the Office for National Statistics on request, June 2016. Similar data can be found here: http://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/cancerregistrationstatisticsengland/previousReleases.
  2. Data were provided by ISD Scotland on request, May 2016. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications/.
  3. Data were provided by the Welsh Cancer Intelligence and Surveillance Unit, Health Intelligence Division, Public Health Wales on request, June 2016. Similar data can be found here: http://www.wcisu.wales.nhs.uk.
  4. Data were provided by the Northern Ireland Cancer Registry on request, May 2016. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.

About this data

Data is for UK, 2012-2014, ICD-10 C52

Last reviewed:

Vaginal cancer incidence rates have decreased by 14% in females in Great Britain since the late 1970s.[1-3]

European age-standardised Open a glossary item (AS) incidence rates rates have decreased by 14% between 1979-1981 and 2011-2013.

Vaginal Cancer (C52), European Age-Standardised Incidence Rates, Females, Great Britain, 1979-2013

ASR calculated with ESP2013. Not comparable with ASRs calculated with ESP1976.

Over the last decade in the UK (between 2002-2004 and 2011-2013), vaginal cancer AS incidence rates in females have remained stable.[1-4]

Vaginal Cancer (C52), European Age-Standardised Incidence Rates, Females, UK, 1993-2013

ASR calculated with ESP2013. Not comparable with ASRs calculated with ESP1976.

Vaginal cancer incidence trends probably reflect changing prevalence of risk factors, with recent incidence trends influenced by risk factor prevalence in years past, and current risk factor prevalence perhaps not to show an impact for some time.[5,6]

Vaginal cancer incidence rates have overall remained stable for most of the broad age groups in Great Britain since the late 1970s.[1-3] In females aged 80+ rates overall decreased by 39%, though this includes a decrease until the late 1990s, and a subsequent increase.

Vaginal Cancer (C52), European Age-Standardised Incidence Rates, by Age, Females, Great Britain, 1979-2013

ASR calculated with ESP2013. Not comparable with ASRs calculated with ESP1976.

References

  1. Data were provided by the Office for National Statistics on request, July 2015. Similar data can be found here: http://www.ons.gov.uk/ons/rel/vsob1/cancer-statistics-registrations--england--series-mb1-/index.html.
  2. Data were provided by ISD Scotland on request, April 2015. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications/index.asp.
  3. Data were provided by the Welsh Cancer Intelligence and Surveillance Unit on request, February 2015. Similar data can be found here: http://www.wales.nhs.uk/sites3/page.cfm?orgid=242&pid=59080.
  4. Data were provided by the Northern Ireland Cancer Registry on request, June 2014. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.
  5. Hemminki K, Li X, Vaittinen P. Time trends in the incidence of cervical and other genital squamous cell carcinomas and adenocarcinomas in Sweden, 1958-1996. Eur J Obstet Gynaecol 2002;101:64-69.
  6. Kurdgelashvili G, Dores GM, Srour SA, et al. Incidence of potentially human papillomavirus-related neoplasms in the United States, 1978 to 2007. Cancer 2013; 119(12):2291-2299.
Last reviewed:

More than 90% of primary tumours Open a glossary item in the vagina are carcinomas Open a glossary item, and, of these, almost 80% are squamous cell carcinoma [glossary - squamous cell cancer] and about 14% are adenocarcinomas Open a glossary item. [1,2] Adenocarcinomas are more common in childhood and early adulthood, accounting for the vast majority of carcinomas diagnosed in women under 20.[1,2] A small proportion of adenocarcinomas are clear cell carcinomas arising in women exposed to diethylstilboestrol (DES) in utero. The highest incidence of clear cell carcinoma arises in young women in their late teens and early 20s.[3] Melanomas and sarcomas account for about 7% of primary vaginal tumours.[1]

References

  1. Creasman WT, Phillips JL, Menck HR. The National cancer data base report on cancer of the vagina. Cancer 1998; 83:1033.
  2. Beller U, Sideri M, Maisonneuve P, et al. Carcinoma of the vagina. Int J Gynaecol Obstet 2003; 83 Suppl 1:27-39.
  3. Laitman CJ. DES exposure and the aging woman: mothers and daughters. Curr Womens Health Rep 2002; 2(5):390-3.
Last reviewed:

The lifetime risk of developing vaginal cancer is around 1 in 1,270 for women, in 2012 in the UK.[1]

The lifetime risk for vaginal cancer has been calculated on the assumption that the possibility of having more than one diagnosis of vaginal cancer over the course of a lifetime is very low (‘Current Probability’ method).[2]

References

  1. Lifetime risk estimates calculated by the Statistical Information Team at Cancer Research UK. Based on data provided by the Office of National Statistics, ISD Scotland, the Welsh Cancer Intelligence and Surveillance Unit and the Northern Ireland Cancer Registry, on request, December 2013 to July 2014.
  2. Esteve J, Benhamou E and Raymond L. Descriptive epidemiology. IARC Scientific Publications No.128, Lyon, International Agency for Research on Cancer, pp 67-68 1994.
Last reviewed:

There is evidence for an association between vaginal cancer incidence and deprivation in England.[1] England-wide data for 2006-2010 show European age-standardised Open a glossary item incidence rates are 85% higher for females living in the most deprived areas compared with the least deprived.[1]

Vaginal Cancer (C52), European Age-Standardised Incidence Rates by Deprivation Quintile, Females, England, 2006-2010

The estimated deprivation gradient in vaginal cancer incidence between females living in the most and least deprived areas in England has not changed in the period 1996-2010.[1] It has been estimated that there would have been 50 fewer cancer cases each year in England during 2006-2010 if all females experienced the same incidence rates as the least deprived.[1]

Last reviewed:

Cancer Statistics Explained

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