Chronic myeloid leukaemia (CML) mortality statistics

Deaths

Deaths from chronic myeloid leukaemia, 2014, UK

 

Proportion of all deaths

Percentage chronic myeloid leukaemia is of total cancer deaths, 2014, UK

 

Age

Peak rate of chronic myeloid leukaemia deaths, 2012-2014, UK

 

 

Trend over time

Chronic myeloid leukaemia mortality rates have decreased by 71% since the early 1970s, UK

 

Chronic myeloid leukaemia (CML) accounts for less than 1% of all cancer deaths in the UK (2014), for both males and females.[1-3]

In 2014, there were 219 CML deaths in the UK: 114 (52%) in males and 105 (48%) in females, giving a male:female ratio of around 11:10.[1-3] The crude mortality rate shows that there is less than 1 CML death for every 100,000 males in the UK, and less than 1 for every 100,000 females.

The European age-standardised Open a glossary item mortality rates (AS rates) do not differ significantly between the constituent countries of the UK for either sex. [1-3]

Chronic Myeloid Leukaemia (C92.1), Number of Deaths, Crude and European Age-Standardised (AS) Mortality Rates per 100,000 Population, UK, 2014

England Wales Scotland Northern Ireland UK
Male Deaths 91 10 10 3 114
Crude Rate 0.3 0.7 0.4 0.3 0.4
AS Rate 0.4 0.8 0.4 0.7 0.5
AS Rate - 95% LCL 0.4 0.3 0.2 -0.1 0.4
AS Rate - 95% UCL 0.5 1.2 0.7 1.4 0.5
Female Deaths 85 8 9 3 105
Crude Rate 0.3 0.5 0.3 0.3 0.3
AS Rate 0.3 0.4 0.3 0.3 0.3
AS Rate - 95% LCL 0.2 0.1 0.1 -0.0 0.2
AS Rate - 95% UCL 0.4 0.7 0.5 0.7 0.4
Persons Deaths 176 18 19 6 219
Crude Rate 0.3 0.6 0.4 0.3 0.3
AS Rate 0.4 0.6 0.4 0.4 0.4
AS Rate - 95% LCL 0.3 0.3 0.2 0.1 0.3
AS Rate - 95% UCL 0.4 0.8 0.6 0.8 0.4

95% LCL and 95% UCL are the 95% lower and upper confidence limit Open a glossary item around the AS rate

References

  1. Data were provided by the Office for National Statistics on request, November 2015. Similar data can be found here: https://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths/bulletins/deathsregistrationsummarytables/previousReleases.
  2. Data were provided by Information Services Division (ISD) Scotland on request, November 2015. Similar data can be found here: http://www.nrscotland.gov.uk/statistics-and-data/statistics/statistics-by-theme/vital-events/vital-events-reference-tables.
  3. Data were provided by the Northern Ireland Statistics and Research Agency on request, November 2015. Similar data can be found here: http://www.nisra.gov.uk/demography/default.asp2.htm.
Last reviewed:

Chronic myeloid leukaemia (CML) mortality is strongly related to age, with the highest mortality rates being in older males and females. In the UK in 2012-2014, on average each year around half (51%) of deaths were in people aged 80 and over.[1-3]

Age-specific mortality rates rise sharply from around age 60-64, with the highest rates in the 90+ age group. Mortality rates are significantly higher for males than for females in those aged 70-74, when the male:female ratio of age-specific rates (to account for the different proportions of males to females in each age group) is around 25:10.[1-3]

Chronic Myeloid Leukaemia (C92.1), Average Number of Deaths per Year and Age-Specific Mortality Rates, UK, 2012-2014

For most cancer types, mortality by age largely reflects incidence and survival by age, e.g. typically, higher incidence and lower survival in older people results in higher mortality in older people.

References

  1. Data were provided by the Office for National Statistics on request, November 2015. Similar data can be found here: https://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths/bulletins/deathsregistrationsummarytables/previousReleases.
  2. Data were provided by the Information Services Division (ISD) Scotland on request, November 2015. Similar data can be found here: http://www.nrscotland.gov.uk/statistics-and-data/statistics/statistics-by-theme/vital-events/vital-events-reference-tables.
  3. Data were provided by the Northern Ireland Statistics and Research Agency on request, November 2015. Similar data can be found here: http://www.nisra.gov.uk/demography/default.asp2.htm.
Last reviewed:

Chronic myeloid leukaemia (CML) mortality rates have decreased by 71% in the UK since the early 1970s.[1-3] This includes a similar decrease for males and females and for both sexes there has been a period of stability followed by a decrease during this time.

For males, European age-standardised Open a glossary item (AS) mortality rates remained stable between 1971-1973 and1987-1989 and then decreased by 75% between 1987-1989 and 2012-2014. For females, rates remained stable between 1971-1973 and 1987-1989 and then decreased by 74% between 1987-1989 and 2012-2014.

Over the last decade in the UK (between 2003-2005 and 2012-2014), CML AS mortality rates have decreased by 33% for males and females combined, with a larger decrease in males (38%) than in females (29%).[1-3]

Chronic Myeloid Leukaemia (C92.1), European Age-Standardised Mortality Rates, UK, 1971-2014

For most cancer types, mortality trends largely reflect incidence and survival trends, e.g. increased incidence without sufficient survival improvement results in increased mortality.

CML mortality rates have decreased overall for all of  the broad age groups in the UK since the early 1970s.[1-3] The largest decrease has been in people aged 0-24, with rates falling by 94% between 1971-1973 and 2012-2014.

Chronic Myeloid Leukaemia (C92.1), European Age-Standardised Mortality Rates, by Age, Persons, UK, 1971-2014

References

  1. Data were provided by the Office for National Statistics on request, November 2015. Similar data can be found here: https://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths/bulletins/deathsregistrationsummarytables/previousReleases.
  2. Data were provided by the Information Services Division (ISD) Scotland on request, November 2015. Similar data can be found here: http://www.nrscotland.gov.uk/statistics-and-data/statistics/statistics-by-theme/vital-events/vital-events-reference-tables.
  3. Data were provided by the Northern Ireland Statistics and Research Agency on request, November 2015. Similar data can be found here: http://www.nisra.gov.uk/demography/default.asp2.htm.
Last reviewed:

There is evidence for an association between chronic myeloid leukaemia (CML) mortality and deprivation for males in England, but there is no evidence for an association for females.[1] England-wide data for 2007-2011 show European age-standardised Open a glossary item mortality rates are 33% higher for males living in the most deprived areas compared with the least deprived, but for females the rates are similar for those living in the least and most deprived areas.[1]

Chronic Myeloid Leukaemia (C92.1), European Age-Standardised Mortality Rates by Deprivation Quintile, England, 2007-2011

The estimated deprivation gradient in CML mortality for males and females living in the most and least deprived areas in England has not changed in the period 2002-2011.[1] It has been estimated that there would have been around 15 fewer cancer deaths each year in England during 2007-2011 if all people experienced the same mortality rates as the least deprived.[1]

Last reviewed:

Cancer Statistics Explained

See information and explanations on terminology used for statistics and reporting of cancer, and the methods used to calculate some of our statistics.

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