In situ breast carcinoma incidence statistics

Cases

New cases of in situ breast carcinoma, 2014, UK

 

Age

Peak rate of in situ breast carcinoma cases, 2012-2014, UK

Trend since 1970s

In situ breast carcinoma (females only) incidence rates have increased since the late 1970s, GB

 

In 2014, there were 7,900 new cases of in situ breast carcinoma in the UK: 7,868 (99.6%) in females and 32 (0.4%) in males, giving a female:male ratio of around 246:1.[1-4] The crude incidence rate shows that there are 24 new in situ breast carcinoma cancer cases for every 100,000 females in the UK, and 0.1 for every 100,000 males.

The European age-standardised incidence rate (AS rate) Open a glossary item of in situ breast carcinoma in females is significantly higher in England than in Wales, Scotland and Northern Ireland.[1-4] Rates for females in Scotland are lower compared with Wales. There are no other significant differences between the constituent countries of the UK.

In Situ Breast Carcinoma (D05), Number of New Cases, Crude and European Age-Standardised (AS) Incidence Rates per 100,000 Population, UK, 2014

England Wales Scotland Northern Ireland UK
Male Cases 28 1 1 2 32
Crude Rate 0.1 0.1 0.0 0.2 0.1
AS Rate 0.1 0.1 0.0 0.3 0.1
AS Rate - 95% LCL 0.1 -0.1 -0.0 -0.1 0.1
AS Rate - 95% UCL 0.2 0.2 0.1 0.8 0.2
Female Cases 6,824 420 462 162 7,868
Crude Rate 24.8 26.7 16.8 17.3 24.0
AS Rate 26.0 26.2 16.7 18.8 25.0
AS Rate - 95% LCL 25.4 23.7 15.1 15.9 24.5
AS Rate - 95% UCL 26.6 28.7 18.2 21.7 25.6

95% LCL and 95% UCL are the 95% lower and upper confidence limits around the AS Rate Open a glossary item

References

  1. Data were provided by the Office for National Statistics on request, June 2016. Similar data can be found here: http://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/cancerregistrationstatisticsengland/previousReleases.
  2. Data were provided by ISD Scotland on request, May 2016. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications/
  3. Data were provided by the Welsh Cancer Intelligence and Surveillance Unit, Health Intelligence Division, Public Health Wales on request, June 2016. Similar data can be found here: http://www.wcisu.wales.nhs.uk.
  4. Data were provided by the Northern Ireland Cancer Registry on request, May 2016. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.

About this data

Data is for: UK, 2014, ICD-10 D05

Last reviewed:

Female in situ breast carcinoma incidence is related to age, with the highest incidence rates being in females in their 50s and 60s. In the UK in 2012-2014, on average each year almost half (48%) of cases were diagnosed in females aged 60 and over.[1-4

Age-specific incidence rates rise steeply from around age 30-34, peak at age 50-54, drop slightly at age 55-59 before a second peak at 65-69, then decrease steeply until 75-79 and more steadily thereafter.[1-4]

There are too few male in situ breast carcinoma cases each year to examine incidence by age.

In Situ Breast Carcinoma (D05), Average Number of New Cases per Year and Age-Specific Incidence Rates, Females, UK, 2012-2014

For in situ breast carcinoma, most cases are identified through the breast cancer screening programme. Incidence increases rapidly at the age screening starts, as prevalent cases are identified, then falls rapidly at the age routine screening ends.

References

  1. Data were provided by the Office for National Statistics on request, June 2016. Similar data can be found here: http://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/cancerregistrationstatisticsengland/previousReleases.
  2. Data were provided by ISD Scotland on request, May 2016. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications/.
  3. Data were provided by the Welsh Cancer Intelligence and Surveillance Unit, Health Intelligence Division, Public Health Wales on request, June 2016. Similar data can be found here: http://www.wcisu.wales.nhs.uk.  
  4. Data were provided by the Northern Ireland Cancer Registry on request, May 2016. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.

About this data

Data is for UK, 2012-2014, ICD-10 D05

Last reviewed:

Female in situ breast carcinoma incidence rates have increased by 534% in Great Britain since the late 1970s.[1-3] Most of this increase happened between the late 1980s and late 1990s.

European age-standardised (AS) Open a glossary item incidence rates increased by 40% between 1979-1981 and 1988-1990, then by almost two-and-a-half times (142% increase) between 1988-1990 and 1997-1999. Rates increased by 87% between 1997-1999 and 2011-2013.[1-3]

In Situ Breast Carcinoma (D05), European Age-Standardised Incidence Rates, Females, Great Britain, 1979 -2013

ASR calculated with ESP2013. Not comparable with ASRs calculated with ESP1976.

Over the last decade in the UK (between 2002-2004 and 2011-2013), female in situ breast carcinoma AS incidence rates have increased by 41%.[1-4]

In Situ Breast Carcinoma (D05), European Age-Standardised Incidence Rates, Females, UK, 1993-2013

ASR calculated with ESP2013. Not comparable with ASRs calculated with ESP1976.

Female in situ breast carcinoma incidence trends largely reflect the introduction of the UK breast screening programmes in the late 1980s, and subsequent extensions to the screening-eligible age group and improvements in screening methods.[5]

Female in situ breast carcinoma incidence rates have overall increased for all broad age groups in Great Britain since the late 1970s.[1-3] The largest increases have been in females of screening age, with European AS incidence rates increasing more than nine-fold in females aged 50-64 (890% increase), and more than 11-fold in those aged 65-69 (1074% increase), between 1979-1981 and 2011-2013.

In Situ Breast Carcinoma (D05), European Age-Standardised Incidence Rates, Females, by Age, Great Britain, 1979-2013

ASR calculated with ESP2013. Not comparable with ASRs calculated with ESP1976.

References

  1. Data were provided by the Office for National Statistics on request, July 2015. Similar data can be found here: http://www.ons.gov.uk/ons/rel/vsob1/cancer-statistics-registrations--england--series-mb1-/index.html.  
  2. Data were provided by ISD Scotland on request, April 2015. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications/index.asp.  
  3. Data were provided by the Welsh Cancer Intelligence and Surveillance Unit on request, February 2015. Similar data can be found here: http://www.wales.nhs.uk/sites3/page.cfm?orgid=242&pid=59080.  
  4. Data were provided by the Northern Ireland Cancer Registry on request, March 2015. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.
  5. Glover JA, Bannon FJ, Hughes CM, et al. Increased diagnosis and detection rates of carcinoma in situ of the breast. Breast Cancer Res Treat. 2012;133(2):779-84. 
Last reviewed:

Most in situ breast carcinoma cases are intraductal, and there is a much smaller proportion of lobular in situ breast carcinomas (2010-2012).[1-4]

A small proportion of cases did not have the specific part of the breast recorded in cancer registry data.[1-4]

Cases and percentages may not sum due to rounding

References

  1. Data were provided by the Office for National Statistics on request, July 2014. Similar data can be found here: http://www.ons.gov.uk/ons/rel/vsob1/cancer-statistics-registrations--england--series-mb1-/index.html.
  2. Data were provided by ISD Scotland on request, April 2014. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications/index.asp.
  3. Data were provided by the Welsh Cancer Intelligence and Surveillance Unit on request, April 2014. Similar data can be found here: http://www.wales.nhs.uk/sites3/page.cfm?orgid=242&pid=59080.
  4. Data were provided by the Northern Ireland Cancer Registry on request, June 2014. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/CancerInformation/.
Last reviewed:

A quarter of women diagnosed with in situ breast carcinoma in England during 2006-2007 live in the least deprived areas of England, while only 13% live in the most deprived areas.[1] A similar distribution of cases by deprivation is also reported for invasive breast cancer.[1]

Last reviewed:

The proportion of incidence cases in White females with in situ breast carcinoma is significantly higher than for Asian or Black females.[1]

A similar ethnic profile is also reported for invasive breast cancer.[2]

Analysis included unknown data. For in situ breast carcinoma, 5,460 cases were identified; 28% had no known ethnicity.

Last reviewed:

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