Brain, other CNS and intracranial tumours mortality statistics

Deaths

Deaths from brain tumour, 2014, UK

 

Proportion of all deaths

Percentage brain tumour is of total cancer deaths, 2014, UK

 

Age

Peak rate of brain tumour deaths, 2012-2014, UK

 

Trend over time

Malignant brain tumour mortality rates have increased by 52% since the early 1970s, UK

 

Brain, other CNS and intracranial tumours are the eighth most common cause of cancer death in the UK (2014), accounting for 3% of all cancer deaths.[1-3] In males, they are the ninth most common cause of cancer death in the UK (3% of all male cancer deaths), whilst they are the seventh most common cause of cancer death in females in the UK (3% of all female cancer deaths).

In 2014, there were 5,223 brain, other CNS and intracranial tumour deaths in the UK: 2,881 (55%) in males and 2,342 (45%) in females, giving a male:female ratio of around 12:10.[1-3] The crude mortality rate Open a glossary item shows that there are 9 brain, other CNS and intracranial tumours deaths for every 100,000 males in the UK, and 7 for every 100,000 females.

The European age-standardised mortality rates Open a glossary item (AS rates) do not differ significantly between the constituent countries of the UK for either sex.[1-3]

Brain, Other CNS and Intracranial Tumours (C70-C72, C75.1-C75.3, D32-D33, D35.2-D35.4, D42-D43, and D44.3-D44.5), Number of Deaths, Crude and European Age-Standardised (AS) Mortality Rates per 100,000 Population, UK, 2014

England Wales Scotland Northern Ireland UK
Male Deaths 2,410 148 244 79 2,881
Crude Rate 9.0 9.7 9.4 8.8 9.1
AS Rate 10.4 10.2 10.5 10.9 10.4
AS Rate - 95% LCL 10.0 8.6 9.2 8.5 10.1
AS Rate - 95% UCL 10.8 11.9 11.8 13.3 10.8
Female Deaths 1,925 132 231 54 2,342
Crude Rate 7.0 8.4 8.4 5.8 7.1
AS Rate 7.1 8.0 8.3 6.3 7.2
AS Rate - 95% LCL 6.8 6.6 7.2 4.6 7.0
AS Rate - 95% UCL 7.4 9.4 9.4 8.0 7.5
Persons Deaths 4,143 271 459 130 5,223
Crude Rate 7.7 8.8 8.6 7.1 8.1
AS Rate 8.4 8.8 9.0 8.2 8.7
AS Rate - 95% LCL 8.1 7.7 8.2 6.8 8.5
AS Rate - 95% UCL 8.6 9.8 9.8 9.6 9.0

95% LCL and 95% UCL are the 95% lower and upper confidence limits Open a glossary item around the AS rate Open a glossary item

Malignant brain tumours (ICD-10 C71) mortality rates throughout the UK shows small but significant variation between health boundaries, with no clear geographical pattern for both males and females; however, as with variation in incidence, it is unknown whether this variation is real or reflects differences in registration practices.[4]

References

  1. Data were provided by the Office for National Statistics on request, November 2015. Similar data can be found here: https://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths/bulletins/deathsregistrationsummarytables/previousReleases.
  2. Data were provided by the Information Services Division (ISD) Scotland on request, November 2015. Similar data can be found here: http://www.nrscotland.gov.uk/statistics-and-data/statistics/statistics-by-theme/vital-events/vital-events-reference-tables.
  3. Data were provided by the Northern Ireland Statistics and Research Agency on request, November 2015. Similar data can be found here: http://www.nisra.gov.uk/demography/default.asp2.htm.
  4. NCIN. Cancer e-Atlas. European Age-Standardised Mortality Rates, UK (England: former Primary Care Trusts; Wales; Scotland: NHS Health Boards; Northern Ireland: Health and Social Care Trusts), 2009-2011.
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Brain, other CNS and intracranial tumours mortality is strongly related to age, with the highest mortality rates being in older males and females. In the UK in 2012-2014, on average each year almost half (47%) of deaths were in people aged 70 and over.[1-3]

Age-specific mortality rates remain relatively stable until around age 25-29, then rise steadily until around age 45-49, and more sharply thereafter, with the highest rates in the 90+ age group. Mortality rates are significantly higher for males than for females in those aged 25-29 and 35-39 to 85-89, and this gap is widest at the ages of 35-39, when the male:female ratio of age-specific  rates (to account for the different proportions of males to females in each age group) is around 18:10.[1-3]

Brain, Other CNS and Intracranial Tumours (C70-C72, C75.1-C75.3, D32-D33, D35.2-D35.4, D42-D43, and D44.3-D44.5), Average Number of Deaths per Year and Age-Specific Mortality Rates, UK, 2012-2014

For most cancer types, mortality by age largely reflects incidence and survival by age, e.g. typically, higher incidence and lower survival in older people results in higher mortality in older people.

References

  1. Data were provided by the Office for National Statistics on request, November 2015. Similar data can be found here: https://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths/bulletins/deathsregistrationsummarytables/previousReleases.
  2. Data were provided by the Information Services Division (ISD) Scotland on request, November 2015. Similar data can be found here: http://www.nrscotland.gov.uk/statistics-and-data/statistics/statistics-by-theme/vital-events/vital-events-reference-tables.
  3. Data were provided by the Northern Ireland Statistics and Research Agency on request, November 2015. Similar data can be found here: http://www.nisra.gov.uk/demography/default.asp2.htm.
Last reviewed:

Malignant brain, other central nervous system (CNS) and intracranial tumours mortality rates have increased by 52% in the UK since the early 1970s.[1-3] This includes a larger increase for males than for females.

For males, European age standardised Open a glossary item (AS) mortality rates increased by 54% between 1971-1973 and 2012-2014. For females, rates increased by 48% in this period.

Malignant Brain, Other CNS and Intracranial Tumours (C70-C72, C75.1-C75.3) European Age-Standardised Mortality Rates, UK, 1971-2014

For most cancer types, mortality trends largely reflect incidence and survival trends, e.g. increased incidence without sufficient survival improvement results in increased mortality.

Over the last decade in the UK (between 2003-2005 and 2012-2014), brain, other CNS and intracranial tumours (malignant, benign, and uncertain or unknown behaviour) mortality rates have remained stable in the UK, for males and females combined and separately.[1-3]

Brain, Other CNS and Intracranial Tumours (C70-C72, C75.1-C75.3, D32-D33, D35.2-D35.4, D42-D43, D44.3-D44.5), European Age-Standardised Mortality Rates, UK, 1993-2014

Malignant brain, other CNS and intracranial tumours mortality rates have increased overall for people aged 60-69 and over in the UK since the early 1970s, but decreased for the younger age groups.[1-3] The largest increase by has been in people aged 80+, with rates increasing more than 18-fold between 1971-1973 and 2012-2014. The largest decrease has been in people aged 25-49, with rates decreasing by 25% between 1971-1973 and 2012-2014.

Malignant Brain, Other CNS and Intracranial Tumours (C70-C72, C75.1-C75.3), European Age-Standardised Mortality Rates, by Age, Persons, UK, 1971-2014

References

  1. Data were provided by the Office for National Statistics on request, November 2015. Similar data can be found here: https://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths/bulletins/deathsregistrationsummarytables/previousReleases.
  2. Data were provided by the Information Services Division (ISD) Scotland on request, November 2015. Similar data can be found here: http://www.nrscotland.gov.uk/statistics-and-data/statistics/statistics-by-theme/vital-events/vital-events-reference-tables.
  3. Data were provided by the Northern Ireland Statistics and Research Agency on request, November 2015. Similar data can be found here: http://www.nisra.gov.uk/demography/default.asp2.htm.
Last reviewed:

There is no evidence for an association between brain, other CNS and intracranial tumour mortality and deprivation for either males or females in England.[1] England-wide data for 2007-2011 show European age-standardised Open a glossary item mortality rates are similar for both males and females living in the most deprived areas compared with the least deprived.[1]

Brain, Other CNS and Intracranial Tumours (C70-C72,C751-3,D32-D33,D352-4,D42-D43,D443-5), European Age-Standardised Mortality Rates by Deprivation Quintile, England, 2007-2011

The estimated deprivation gradient in brain, other CNS and intracranial tumour mortality between people living in the most and least deprived areas in England has not changed in the period 2002-2011.[1]

Last reviewed:

Brain and other CNS cancer (C70-C72 only) are the 11th most common cause of cancer death in Europe, with around 45,000 deaths in 2012 (3% of the total). In Europe (2012), the highest World age-standardised Open a glossary item mortality rates for brain and other CNS cancer are in Albania for both men and women; the lowest rates are in Cyprus for men and Malta for women. UK mortality rates for brain and other CNS cancer are estimated to be the 20th lowest in males in Europe, and 15th lowest in females.[1] These data are broadly in line with Europe-specific data available elsewhere.[2]

Brain and other CNS cancer (C70-C72 only) are the 12th most common cause of cancer death worldwide, with more than 189,000 deaths in 2012 (2% of the total). Brain and other CNS cancer mortality rates are highest in Northern Europe and lowest in Western Africa, but this partly reflects varying data quality worldwide.[1]

References

  1. Ferlay J, Soerjomataram I, Ervik M, et al. GLOBOCAN 2012 v1.0, Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 11 [Internet]. Lyon, France: International Agency for Research on Cancer; 2013. Available from: http://globocan.iarc.fr, accessed December 2013.
  2. Ferlay J, Steliarova-Foucher E, Lortet-Tieulent J, et al.Cancer incidence and mortality patterns in Europe: Estimates for 40 countries in 2012. European Journal of Cancer (2013) 49, 1374-1403.
Last reviewed:

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