Bladder cancer survival statistics

77% of men survive bladder cancer for at least one year, and this is predicted to fall to 57% surviving for five years or more, as shown by age-standardised Open a glossary item net survival for patients diagnosed with bladder cancer during 2010-2011 in England and Wales.[1] Survival for women is considerably lower, with 62% surviving for one year or more, and 46% predicted to survive for at least five years. The male survival advantage is seen in many countries across Europe,[2] and may be attributed in part to earlier diagnosis in men.[3,4]

Bladder Cancer (C67), Age-Standardised One-, Five- and Ten-Year Net Survival, Adults (Aged 15-99), England and Wales, 2010-2011

1-Year Survival (%) 5-Year Survival (%) 10-Year Survival (%)
Men Net Survival 76.6 56.9 54.3
95% LCL 76.6 56.7 53.9
95% UCL 76.6 57.1 54.8
Women Net Survival 61.6 45.6 39.5
95% LCL 61.5 45.2 38.8
95% UCL 61.8 46.1 40.2
Adults Net Survival 72.4 53.7 50.2
95% LCL 72.4 53.6 49.8
95% UCL 72.4 53.9 50.6

95% LCL and 95% UCL are the 95% lower and upper confidence limits Open a glossary item

Five- and ten-year survival is predicted using an excess hazard statistical model

Bladder cancer survival gradually continues to fall beyond five years after diagnosis, with the rate of decline being greater for women than for men. 54% of men and 40% of women are predicted to survive their disease for ten years or more, as shown by age-standardised net survival for patients diagnosed with bladder cancer during 2010-2011 in England and Wales.[1] Out of 20 common cancers in England and Wales, ten-year survival for bladder cancer ranks 11th highest overall.

Bladder Cancer (C67), Net Survival up to Ten Years after Diagnosis, Adults (Aged 15-99), England and Wales, 2010-2011

Survival for bladder cancer is reported in Scotland and Northern Ireland,[5,6] though it is difficult to make survival comparisons between countries due to different methodologies and criteria for including patients in analyses. There might also be underlying variation in classification and coding practices between UK countries.

References

  1. Cancer Research UK Cancer Survival Group, London School of Hygiene and Tropical Medicine. Personal communication, 2014.
  2. Sant M, Allemani C, Santaquilani M, et al. EUROCARE-4. Survival of cancer patients diagnosed in 1995-1999. Results and commentary. Eur J Cancer 2009;45:931-91.
  3. Ries LAG, Harkins D, Krapcho M, et al. SEER Cancer Statistics Review, 1975-2003. Maryland, US: National Cancer Institute; 2006.
  4. Mungan NA, Aben KK, Schoenberg MP, et al. Gender differences in stage-adjusted bladder cancer survival. Urology 2000;55(6):876-80.
  5. ISD Scotland. Trends in Cancer Survival 1983-2007.
  6. Northern Ireland Cancer Registry. Incidence & Survival 1993-2012.
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Five-year survival for bladder cancer is generally higher in younger men and women and decreases with increasing age. Five-year net survival in men ranges from 74% in 15-49 year-olds to 40% in 80-99 year-olds for patients diagnosed with bladder cancer in England during 2007-2011.[1] In women, five-year survival ranges from 59% in 50-59 year-olds to 31% in 80-99 year-olds.

Bladder Cancer (C67), Five-Year Net Survival by Age, England, 2007-2011

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Bladder cancer survival trends are difficult to interpret because of changes to classification and coding practices affecting the definition of invasive carcinoma of the bladder.The decrease in bladder cancer survival since the 1990s is likely to be due to an increasing proportion of bladder tumours now being coded as in situ or uncertain.

One-year age-standardised net survival for bladder cancer in men has increased from 63% during 1971-1972 to 80% during 1990-1991 and then decreased to 77% during 2010-2011 in England and Wales.[1] In women, one-year survival has increased from 53% to 70% and then decreased to 62% over the same time periods.

Bladder Cancer (C67), Age-Standardised One-Year Net Survival, Adults (Aged 15-99), England and Wales, 1971-2011

Five-year age-standardised net survival for bladder cancer in men has increased from 41% during 1971-1972 to 63% during 1990-1991 and then decreased to a predicted survival of 57% during 2010-2011 in England and Wales.[1] In women, five-year survival has increased from 35% to 55% and then decreased to 46% over the same time periods.

Bladder Cancer (C67), Age-Standardised Five-Year Net Survival, Adults (Aged 15-99), England and Wales, 1971-2011

Five-year survival for 2010-2011 is predicted using an excess hazard statistical model

Ten-year age-standardised net survival for bladder cancer in men has increased from 34% during 1971-1972 to 54% during 1990-1991 and remained stable at a predicted survival of 54% during 2010-2011 in England and Wales.[1] In women, ten-year survival has increased from 29% to 49% and then decreased to 40% over the same time periods. Overall, half of people diagnosed with bladder cancer today are predicted to survive their disease for at least ten years.

Bladder Cancer (C67), Age-Standardised Ten-Year Net Survival, Adults (Aged 15-99), England and Wales, 1971-2011

Ten-year survival for 2005-2006 and 2010-2011 is predicted using an excess hazard statistical model

References

  1. Cancer Research UK Cancer Survival Group, London School of Hygiene and Tropical Medicine. Personal communication, 2014.
Last reviewed:

Survival for bladder cancer is related to stage of the disease at diagnosis. The majority of patients are diagnosed at Stages I or II.

One-year relative survival for bladder cancer (including in situ and unknown or uncertain behaviour tumours [C67, D090 and D414]) is highest for patients presenting at Stage I, with 97% of men and 96% of women surviving their disease for at least one year for patients diagnosed during 2006-2010 in the former Anglia Cancer Network.[1] One-year survival is lowest for those diagnosed with Stage IV disease (26% for men and 25% for women).

For patients diagnosed at Stage II, one-year relative survival is significantly higher for men than for women, with an absolute survival difference Open a glossary item of 17 percentage points. One-year survival is not significantly different between men and women at any of the other stages.

Bladder Cancer (C67, D090 and D414), One-Year Relative Survival by Stage, Adults (Aged 15-99 Years), Former Anglia Cancer Network, 2006-2010

Relative survival can be greater than 100% because it accounts for background mortality. A relative survival figure greater than 100 indicates that people diagnosed have a better chance of surviving one or five years after diagnosis than the general population

Five-year relative survival for bladder cancer in men ranges from 89% at Stage I to 9% at Stage IV for patients diagnosed during 2002-2006 in the former Anglia Cancer Network.[1] In women, five-year survival ranges from 86% at Stage I to 11% at Stage IV. There are no significant differences in five-year survival between men and women at any of the stages.

Bladder Cancer (C67, D090 and D141), Five-Year Relative Survival by Stage, Adults (Aged 15-99 Years), Former Anglia Cancer Network, 2002-2006

In this section, survival by stage is provided for the former Anglia Cancer Network in the east of England.[2]

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