A trial looking at genetic factors that affect how breast cancer grows and develops (GENFABRCA)
Please note - this trial is no longer recruiting patients. We hope to add results when they are available.
This study is looking at genetic factors that might affect how breast cancer cells develop, grow and respond to treatment.
Many breast cancers respond very well to treatment. But this is not always the case and sometimes breast cancer comes back. Doctors want to understand more about why this happens.
- How breast cancer develops
- Why some breast cancers grow more quickly than others
- How well different breast cancers respond to treatment
In the long term this may help doctors improve the treatment for breast cancer.
Who can enter
You can enter this trial if you
- Have stage 4 breast cancer that has spread to another part of your body
- Are a patient at one of the centres taking part and your doctor asks you if you would like to join the study
- Are well enough to take part
- Are female
- Are from a white ethnic group (Your genes depend on your ethnic group, and the researchers want to make sure that the women in this trial are as similar as possible)
You cannot enter this trial if you
- Have already taken part in another genetic study
This study will recruit 900 women with advanced breast cancer. If you are eligible to take part, the research team may ask you if you would like to join the study.
First a researcher will ask you some questions about yourself and your family history of cancer. This interview will take about 30 minutes.
The doctors will also take a blood sample. They will use this sample to look for genes that may affect how breast cancer develops and grows, and how well different breast cancers respond to treatment. This is for research only and the results won’t affect the treatment you have.
The researchers would like to look at the sample of your cancer that was kept by the hospital when you had your biopsy or surgery. This will help them find out more about any genetic changes within the cancer cells.
If you agree, the researchers will also collect information about your breast cancer and your treatment. They will get this information from your medical notes.
You will have an interview with the researchers when you join the trial. You can either have this during a hospital clinic visit, or the researchers can come to your home. They will take a blood sample at the same time. You won’t have to make any extra trips to the hospital as a result of taking part in this trial.
There are no treatments in this trial. You may get a small bruise where your blood sample is taken, but apart from that there aren’t any side effects.
Location of trialCLOSED
For more information
Please note: we cannot help you to join a specific trial. Unless we state otherwise in this trial summary, you need to print this page and take it to your own doctor to discuss.
Cancer Research UK
407 St John Street
Question about cancer? Contact our information nurse team