Read article A study looking at a new test to find out the risk of bowel cancer coming back - PARSC
This is a study using a new test to help find the risk of cancer of the large bowel (colon) coming back after surgery.
Doctors usually treat cancer of the large bowel (colon) with surgery. After surgery your doctor may recommend chemotherapy if there is a high risk of your cancer coming back.
We know from research that it is not always clear what the risk of bowel cancer coming back is. So researchers are looking for better ways to find this out.
The researchers want to use a test that looks at the actions of genes in the cancer cells. The results may help to show the risk of the cancer coming back more accurately.
The aims of this study are to see if this test
- Can identify those people with bowel cancer who are at a high risk of their cancer coming back
- Changes the way doctors decide about treating people with bowel cancer after surgery
Please note you may not get any benefit if you take part in this study, but your taking part may help others who have bowel cancer in the future.
Recruitment
Phase
Who can enter
You can enter this trial if you
- Have the most common type of bowel cancer (adenocarcinoma) of the large bowel (colon)
- Have cancer that has grown through the wall of the bowel but has not spread to nearby lymph nodes (stage 2)
- Are to have surgery to remove your cancer
- Are at least 18 years old
You cannot enter this trial if you
- Have had chemotherapy to shrink the cancer before surgery (this is called ‘neoadjuvant treatment’)
- Have had, or have, another cancer apart from basal cell cancer or carcinoma in situ of the cervix
Trial design
This is an international study. It will recruit 600 people. Everyone taking part will have surgery to remove their bowel cancer. After surgery your doctor will treat you according to recommended national guidelines.
When you have surgery to remove your cancer, the doctor will send a small part of the cancer tissue to the study team. The study team will use a new test to look at how the genes in the cancer cells are working.
Neither you nor your doctor will know the results of this test.
Hospital visits
There are no extra hospital visits if you take part in this study.
Side effects
The side effects of your surgery will depend on how big your operation is. Your doctor will discuss this with you. There are no side effects from taking part in the trial itself.
You can find more about surgery for colon cancer on CancerHelp UK.
Location of trial
For more information
Please note: we cannot help you to join a specific trial. Unless we state otherwise in this trial summary, you need to print this page and take it to your own doctor to discuss.
Find out how to join a trial or contact our cancer information nurses for other questions about cancer by phone (0808 800 4040), by email, or at
Cancer Research UK
Angel Building
407 St John Street
London
EC1V 4AD
Chief Investigator
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How to take part
Read more about how to join a clinical trial
