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Where this information about genes and inherited risk comes from

This page tells you about the major sources of information that we use to put together this section of CancerHelp UK.

 

About CancerHelp UK information

All our information is checked by cancer specialists. The names of our specialist reviewers are at the end of this list. We also try to find patients to review all our sections. If you have had cancer gene testing because you are thought to be at high risk (and are a resident of the UK) you can help us by becoming a reviewer. Write to us by clicking on the 'contact us' button on the righthand side of this page.

 

Websites

Cancer Research UK
CancerStats Series

UK Genetic testing network (UKGTN) Website (Accessed August 2013)
Has a database of the genetic tests available in the UK.

Clinical molecular genetics society (CMGS)
The CMGS is part of British Society for Human Genetics
Contains a list of the genetic laboratories.

Genetics home reference website (American) (accessed Jan 2008)

National Office of Statistics
The Health statistics section has information about the latest trends in the health of the UK
(Office for National Statistics, Health Statistics Quarterly Autumn 2000 p78)

 

Books

Roger J.B. King and Mike w Robins
Cancer Biology
(3rd edition)
Pearson – Prentice Hall
ISBN (13): 9780131294547

De Vita, V.T., Hellman, S. and Rosenberg S.A.
Principles and practice of oncology (8th edition)
Lippincott, Williams and Wilkins, 2008

Tobias J and Hochhauser D
Cancer and its management (6th edition)
Blackwell Science, 2010
ISBN 978-1-4051-7015-4

 

UK and international guidelines

NICE
Familial breast cancer: the classification and care of women at risk of familial breast cancer in primary, secondary and tertiary care (partial update of CG14) (October 2006)

MG Dunlop (British Society for Gastroenterology)
Guidance on gastrointestinal surveillance for hereditary non-polyposis colorectal cancer, familial adenomatous polypolis, juvenile polyposis, and Peutz-Jeghers syndrome.

Gut
Volume 51 Supplement 5:V21-7. Oct 2002

MG Dunlop (British Society for Gastroenterology)
Guidance on large bowel surveillance for people with two first degree relatives with colorectal cancer or one first degree relative diagnosed with colorectal cancer under 45 years.

Gut
Volume 51 Supplement 5:V17-20. Oct 2002

 

Articles and reviews

K Hemminki et al
Familial risks for cancer as the basis for evidence-based clinical referral and Counselling.

The Oncologist
Volume 13, pp239-247. March 2008

JE Garber and K Offit
Hereditary cancer predisposition syndromes.

Journal of Clinical Oncology
Volume 10;23 (2) pp 276-92 January 2005

 

Specialist Reviewers

Ms. Tara Clancy (Consultant Genetic Counsellor/Honorary Senior Lecturer) 
Prof. Gareth Evans
Dr Paul Pharoah, PhD, FRCP (Consultant in public health medicine)

 

Diagrams

Dee McLean - McDee Art, Medical Illustration

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Updated: 19 August 2013