A trial comparing chemotherapy with no further treatment after surgery to remove sarcoma of the womb

Cancer type:

Soft tissue sarcoma




Phase 3

This trial was for women who have had surgery to remove their womb to treat a type of cancer called leiomyosarcoma. The trial compared chemotherapy after surgery with no further treatment. Cancer Research UK supported this trial.

More about this trial

If you have your womb removed (a hysterectomy Open a glossary item) as treatment for leiomyosarcoma, you are closely followed up afterwards to check for signs of the cancer coming back.

Most women will remain cancer free, but sometimes the cancer does come back. If this happens, you may have chemotherapy. There are several chemotherapy drugs that doctors can use, including a combination of the 2 drugs gemcitabine and docetaxel (Taxotere), and another drug called doxorubicin.

In this trial, researchers wanted to see if having these chemotherapy drugs after surgery to remove leiomyosarcoma reduced the chance of the cancer coming back.

Summary of results

This trial closed early as the researchers were unable to get enough women to take part. Because of this the trial team are not able to produce any significant results.

Recruitment start:

Recruitment end:

How to join a clinical trial

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Chief Investigator

Dr Helen Hatcher

Supported by

Cancer Research UK
European Organisation for Research and Treatment of Cancer (EORTC)
Experimental Cancer Medicine Centre (ECMC)
NIHR Clinical Research Network: Cancer

Other information

This is Cancer Research UK trial number CRUK/11/051.

Questions about cancer? Contact our information nurses

Freephone 0808 800 4040

Last review date

CRUK internal database number:


Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Around 1 in 5 people take part in clinical trials

3 phases of trials

Around 1 in 5 people diagnosed with cancer in the UK take part in a clinical trial.

Last reviewed:

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